Results 51 to 60 of about 685,091 (269)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Relay intercropping can efficiently support weed management in cereal-based cropping systems when appropriate legume species are chosen [PDF]

, 2022
Federico Leoni, Mariateresa Lazzaro, Matteo Ruggeri, Stefano Carlesi, P. Meriggi, Anna‐Camilla Moonen   +5 more
openalex   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

A Method for Estimating Soybean Sowing, Beginning Seed, and Harvesting Dates in Brazil Using NDVI-MODIS Data

Remote Sensing
Brazil, as a global player in soybean production, contributes about 35% to the world’s supply and over half of its agricultural exports. Therefore, reliable information about its development becomes imperative to those who follow the market.
Cleverton Tiago Carneiro de Santana, Ieda Del’Arco Sanches, Marcellus Marques Caldas, Marcos Adami   +3 more
doaj   +1 more source

Resource Productivity under Yam Based Crop Mixture in Crude and Non-Crude Oil Producing Communities of Imo State, Nigeria

Agricultura Tropica et Subtropica, 2014
A study on resource productivity under yam based crop mixture (YBCM) in crude and non-crude oil communities was conducted in Imo State, Nigeria. The study assessed food crops’ outputs, evaluated costs and returns, and determined the allocative efficiency
Nwosu Canice Sonny, Chidebelu Sonny Angus Nnaemeka Dixie   +1 more
doaj   +1 more source

Prediction of vine vigor and precocity using data and knowledge-based fuzzy inference systems

OENO One, 2012
Aims: The evolution of the economic and environmental context (low-input management practices, increase of energy cost and climate change) requires adaptation and/or optimization of winegrower’s practices in order to elaborate competitive and yet still ...
Cécile Coulon-Leroy, Brigitte Charnomordic, Dominique Rioux, Marie Thiollet-Scholtus, Serge Guillaume   +4 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Feeding preferences of Phyllotreta herbivores to winter rape and chosen weeds

Plant Protection Science, 2009
In model experiments with leaf disks from Brassica napus L. subsp. napus and Thlaspi arvense L. and Sinapis arvensis L. in spring periods (May-June) of 2006-2007 feeding preferences of Phyllotreta herbivores to the above-mentioned crop and two common ...
Jindra Štolcová
doaj   +1 more source