Results 51 to 60 of about 415,102 (268)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efectos de la densidad de cultivo y de proteína en la dieta sobre el desempeño del capaz (Pimelodus grosskopfii) en estanques

open access: yesMutis, 2019
La diversificación de la piscicultura colombiana se restringe sobre aquellas especies calificadas como promisorias. En el grupo de los silúridos se tienen representantes sobre los que se ha logrado estabilizar algún nivel de constante esfuerzo ...
Silvia Cristina Carrera
doaj   +1 more source

3-D Modeling of Tomato Canopies Using a High-Resolution Portable Scanning Lidar for Extracting Structural Information

open access: yesSensors, 2011
In the present study, an attempt was made to produce a precise 3D image of a tomato canopy using a portable high-resolution scanning lidar. The tomato canopy was scanned by the lidar from three positions surrounding it.
Fumiki Hosoi   +2 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Retrieval of Leaf Area Index for Wheat and Oilseed Rape Based on Modified Water Cloud Model and SAR Data

open access: yesAgronomy
The accurate and timely determination of crop leaf area indices (LAIs) assists in making agricultural decisions. The objective of this study was to estimate crop LAIs using C-band RADARSAT-2 synthetic aperture radar (SAR) datasets and a modified water ...
Xiyue Yang   +5 more
doaj   +1 more source

Electrosaving system of stable management of crop cultivation in highlands and lowlands

open access: yesBudownictwo o Zoptymalizowanym Potencjale Energetycznym, 2019
Agriculture is one of the strategic spheres of the economy in highland and lowland regions, the main impact of its development by farmers isthe management of stable regimes of cultivating crops.
Gevorg Veranyan   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Home - About - Disclaimer - Privacy