Results 41 to 50 of about 9,281,721 (252)
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Ciência Rural, 2002 Na investigação das relações ecológicas entre as espécies, observou-se que certos animais, principalmente insetos, alimentavam-se de sementes de plantas daninhas antes e depois da sua deiscência, reduzindo a entrada de sementes no banco de sementes do ...
Alvadi Antonio Balbinot Jr. +3 more
doaj +1 more source
Integrated Crop Management for Alfalfa [PDF]
, 1999 Integrated crop management (ICM) is a management strategy where producers assess the series of familiar crop production steps necessary for producing a crop, evaluating alternative practices for practicality, cost/return considerations, and environmental
Barnhart, Stephen, Stephen K. Barnhart
core +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Fungicide Resistance Management in West Australia’s Wheatbelt
Scientific DataBarley growers from the West Australia Wheatbelt were invited to share information on their fungicide resistance management strategies. The study aimed to identify gaps in growers’ knowledge about issues like fungicide resistance and the objective and/or
Toto Olita +5 more
doaj +1 more source
Use of Crop Models to Evaluate Crop Management [PDF]
, 1996 Crop growth models are computer programs that compute daily growth of corn and soybeans based on daily weather (max/min temperature, rainfall, solar radiation) and management practices (planting date, variety, population, fertility, irrigation).
Batchelor, William, William D. Batchelor
core +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
BMC BiologyBackground An understanding of plant pathogen evolution is important for sustainable management of crop diseases. Plant pathogen populations must maintain adequate heritable phenotypic variability to survive.
Mark C. Derbyshire +15 more
doaj +1 more source
Plant ionome diagnosis using sound balances: case study with mango (Mangifera Indica)
Frontiers in Plant Science, 2013 Plant ionomes and soil nutrients are commonly diagnosed in agronomy using concentration and nutrient ratio ranges. However, both diagnoses are biased by redundancy of information, subcompositional incoherence and non-normal distribution inherent to ...
Serge-Étienne eParent +3 more
doaj +1 more source