Results 181 to 190 of about 910,592 (309)

The Global Gridded Crop Model Intercomparison phase 1 simulation dataset. [PDF]

Sci Data, 2019
Müller C, Elliott J, Kelly D, Arneth A, Balkovic J, Ciais P, Deryng D, Folberth C, Hoek S, Izaurralde RC, Jones CD, Khabarov N, Lawrence P, Liu W, Olin S, Pugh TAM, Reddy A, Rosenzweig C, Ruane AC, Sakurai G, Schmid E, Skalsky R, Wang X, de Wit A, Yang H.   +24 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Establishment of a Generalizable Industrial Crop Model for Microwave Extraction of Unsaturated Fatty Acids. [PDF]

Int J Anal Chem
Chen J, Lu D, Chen S, Liu S, Zhang Y, Zhan C.   +5 more
europepmc   +1 more source

Parameterization-induced uncertainties and impacts of crop management harmonization in a global gridded crop model ensemble. [PDF]

PLoS One, 2019
Folberth C, Elliott J, Müller C, Balkovič J, Chryssanthacopoulos J, Izaurralde RC, Jones CD, Khabarov N, Liu W, Reddy A, Schmid E, Skalský R, Yang H, Arneth A, Ciais P, Deryng D, Lawrence PJ, Olin S, Pugh TAM, Ruane AC, Wang X.   +20 more
europepmc   +1 more source

Land Degradation in the Sahel: An Application of Biophysical Modeling in the Optimal Control Setting [PDF]

Low-input farming practices in many parts of the developing world have pushed cultivation onto marginal lands. Sustainability of already fragile ecosystems is threatened.
Lee, John G., Vitale, Jeffrey D.
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Linking genetic markers and crop model parameters using neural networks to enhance genomic prediction of integrative traits. [PDF]

Front Plant Sci
Larue F, Rouan L, Pot D, Rami JF, Luquet D, Beurier G.   +5 more
europepmc   +1 more source

MANAGING PEST RESISTANCE: THE POTENTIAL OF CROP ROTATIONS AND SHREDDING [PDF]

The current debate over resistance management plans mandated by the Environmental Protection Agency for transgenic crops ignores management practices that are complementary to refuge schemes.
Babcock, Bruce A., Secchi, Silvia
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Application of the JULES-crop model and agrometeorological indicators for forecasting off-season maize yield in Brazil. [PDF]

Heliyon
Prudente Junior AC, S Vianna M, Willians K, V Galdos M, Marin FR.   +4 more
europepmc   +1 more source