Results 91 to 100 of about 22,804,860 (345)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Economic Analysis of the Standard Reinsurance Agreement [PDF]

open access: yes
The paper presents an economic analysis of the Standard Reinsurance Agreement (SRA), the contract that governs the relationship between the Federal Crop Insurance Corporation and the private insurance companies that deliver crop insurance products to ...
Dismukes, Robert   +3 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

A REVIEW AND EVALUATION OF WEATHER-CROP YIELD MODELS [PDF]

open access: yes
The purpose of this paper is the relatively limited one of reviewing the literature for models which develop specific relationships between climatic variables and crop yields.
Geigel, Joanne M., Sundquist, W. Burt
core   +1 more source

Predicting crop productivity and adapting the rice plant to changing climates: The importance of modeling [PDF]

open access: yes, 2010
Climate change scenarios are predicting, by the end of the century, an increase in air temperature from 1.1 to 6.4 °C and in air [CO 2] from 600 to 1500 ppm, associated with more frequent submergence and drought events in the rice-growing regions ...
Baron, Christian   +9 more
core  

The macroeconomic cost of catastrophic pollinator declines [PDF]

open access: yes, 2016
We develop a computable general equilibrium (CGE) approach to assess the macroeconomic impacts of productivity shocks due to catastrophic losses of pollination ecosystem services at global and regional scales.
Bauer, Dana Marie, Sue Wing, Ian
core   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Principles of crop modeling and simulation: I. uses of mathematical models in agricultural science

open access: yesScientia Agricola, 1998
Modeling techniques applied to agriculture can be useful to define research priorities and understanding the basic interactions of the soil-plant-atmosphere system.
Dourado-Neto D.   +5 more
doaj  

ON MODELING SYSTEMS OF CROP ACREAGE DEMANDS [PDF]

open access: yes
This article presents an alternative approach to the specification of systems of crop acreage responses. Derived demands for acreages of individual crops are specified as conditional on total crop acreage, and related separability and dynamic ...
Coyle, Barry T.
core   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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