Results 131 to 140 of about 22,804,860 (345)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Smart Coffee: Machine Learning Techniques for Estimating Arabica Coffee Yield
AgriEngineeringCoffee is a global commodity, with Brazil being a major producer, particularly in the Minas Gerais state. This study applied machine learning to predict the Arabica coffee yield in the region, analyzing two groups of cultivars (G1 and G2) using data from
Cleverson Henrique de Freitas +3 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
, 2002 5 slides Provider Notes: Gary Blau's presentation on crop models during Dr. Alan Drysdale's Purdue visit (12/05/2002)
openaire +1 more source
Modeling Pine as a Carbon Sequestering Crop in Arkansas [PDF]
Carbon Sequestration, Loblolly Pine, Carbon Offset, Carbon Policy, Environmental Economics and Policy, Land Economics/Use, Resource /Energy Economics and Policy,
Nalley, Lawton Lanier +2 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Modeling soil organic carbon change in croplands of China [PDF]
, 2003 Using 1990 conditions, we modeled carbon (C) and nitrogen (N) biogeochemical cycles in croplands of China (and, for comparison, the United States) to estimate the annual soil organic-carbon (SOC) balance for all cropland.
Frolking, Steve +7 more
core +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source