Results 141 to 150 of about 7,744,808 (358)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

A GSD ESTIMATION OF THE RELATIVE WORTH OF COVER CROPS IN COTTON PRODUCTION SYSTEMS [PDF]

Cover crops can help reduce the negative environmental impacts of cotton production. Using time series yield data, this study utilizes generalized stochastic dominance to evaluate the relative worth, via risk premiums, of three cover crop and two ...
Giesler, G. Grant, Millhollon, E.P., Paxton, Kenneth W.   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Crops: Illinois General Information, 1985 [PDF]

, 1985
Includes crop review, crop production index, 1960-84; principal crops, acres harvested for grain, 1950-84; record highs through 1984; cash receipts, 1982-83; crop development, 1984; Illinois' position in nation's crop production; aggregate acreage of ...

core  

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Managing Risk with Crop Insurance [PDF]

Every year Iowa farmers face the threat of damage to their crops from drought, hail, flood, insects, and other natural disasters. The U.S.D.A. Risk Management Agency (RMA) and private crop insurance venders have developed a set of insurance programs to ...
Edwards, William M.
core  

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Energy input and output of a rural village in China - the cas of the "Beijing Man village" /District of Beijing [PDF]

, 2006
The rapid development of the economy has created an increasing demand for energy in China. The limited resources of fossil energy are a risk for the development of China.
Cong, Lin, Rahmann, PD Dr. Gerold, Shi, Chenlu, Sun, Prof. Zhenjun, Sun, Yongming, Wei, Xiaoming   +5 more
core  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

FAPRI 2001 U.S. and World Agricultural Outlook [PDF]

Crop Production/Industries, Livestock Production/Industries,
Adams, Gary M., Babcock, Bruce A., Beghin, John C., Brown, D. Scott, de Cara, Stephane, Fabiosa, Jacinto F., Fang, Cheng, Fuller, Frank H., Hart, Chad E., Kaus, Phillip J., Kovarik, Karen, Kruse, John R., Madison, Daniel, Matthey, Holger, Meyer, Seth D., Mohanty, Samarendu, Trujillo, Joe, Westhoff, Patrick C., Willott, Brian, Womack, Abner W., Young, Robert E., II   +20 more
core   +1 more source