Results 191 to 200 of about 7,744,808 (358)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Sustaining the Merry Space farmer with pick-and-eat crop production. [PDF]

NPJ Microgravity
Landon LB, Begerowski SR, Roma PG, Whiting SE, Bell ST, Massa GD.   +5 more
europepmc   +1 more source

Farmers' Willingness to Grow Cover Crops: Examining the Economic Factors of Adoption in Alabama [PDF]

The inclusion of cover crops in cropping systems brings both direct and indirect costs and benefits. The literature has shown that cover crops can improve soil conservation and productivity, potentially improving cash crop yields and decreasing cash crop
Bergtold, Jason S., Duffy, Patricia A., Fewell, Jason E.   +2 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Reconciling crop production, climate action and nature conservation in Europe by agricultural intensification and extensification. [PDF]

Nat Commun
Hua T, Hu X, Austrheim G, Speed JDM, van Oort B, Cherubini F.   +5 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Plant hydraulic traits influencing crop production in water-limited environments. [PDF]

Plant Physiol
Cardoso AA, Andrade MT, Bucior ER, Martins SCV.   +3 more
europepmc   +1 more source

AN ECONOMIC ANALYSIS OF A CORN-SOYBEAN CROP ROTATION UNDER VARIOUS INPUT COMBINATIONS IN SOUTH CENTRAL TEXAS [PDF]

Eight input combinations of commercial fertilizer, insecticides, and herbicides on a corn-soybean crop rotation in the Brazos River Bottom of Texas are evaluated.
Funk, Robert D., Hons, Frank M., Mjelde, James W., Saladino, Vince A.   +3 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Cross-talk within plant niches: endophytic and arbuscular mycorrhizal fungi for sustainable crop production. [PDF]

FEMS Microbiol Rev
Orozco-Mosqueda MDC, Glick BR, Santoyo G.   +2 more
europepmc   +1 more source