Results 81 to 90 of about 589,680 (310)

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

open access: yesFEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara   +3 more
wiley   +1 more source

Development of efficient targeted insertion mediated by CRISPR-Cas12a and homology-directed repair in maize

open access: yesFrontiers in Genome Editing
Targeted insertion (TIN) of transgenic trait cassettes has the potential to reduce timeline and cost for GM product development and commercialization.
Brenden Barco   +46 more
doaj   +1 more source

The Physician‐Scientist Pipeline for Pediatric Rheumatology – Current Landscape and Future Perspectives.

open access: yesArthritis Care &Research, Accepted Article.
Over the past 50 years, the science of pediatric rheumatology has grown exponentially due to an expansion in the understanding of complex rheumatic conditions and a surge in novel targeted therapeutics. Physician‐scientists in the field of pediatric rheumatology have played major roles in these advancements that have improved the care of children ...
Ekemini A. Ogbu   +2 more
wiley   +1 more source

Evaluation of Risk Management Methods for Satsuma Mandarin [PDF]

open access: yes
Simulation of production budgets were used to compare net discounted returns and the distribution of returns under alternative risk-mitigation scenarios. Results indicate that the combination of freeze protection and crop insurance increases expected net
Dozier, William A.   +4 more
core   +1 more source

Using weeds to reduce pest insect numbers in organic vegetable crops - a desk study (OF0329) [PDF]

open access: yes, 2006
At present, weeds and pest insects are two of the major constraints to the production of high quality organic vegetable crops, primarily because the range of control measures available to UK growers is extremely limited.
Grundy, Dr Andrea
core  

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

open access: yesAdvanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio   +11 more
wiley   +1 more source

Do combinations of insecticides and acaricides influence spray droplet formation and the interaction with citrus leaves?

open access: yesJournal of Plant Protection Research, 2019
In agriculture, the mixing of pesticides in tanks is a common practice. However, it is necessary to previse possible physical-chemical implications of this practice, which may affect the efficiency of the treatments performed.
Jaqueline Franciosi Della Vechia   +5 more
doaj   +1 more source

Expression and Functional Analysis of the Plant-Specific Histone Deacetylase HDT701 in Rice

open access: yesFrontiers in Plant Science, 2015
Reversible histone acetylation and deacetylation at the N-terminus of histone tails play a crucial role in regulating eukaryotic gene activity. Acetylation of core histones is associated with gene activation, whereas deacetylation of histone is often ...
Jinhui eZhao   +7 more
doaj   +1 more source

Economic Evaluation of Pesticide Use Externalities in the Cotton Zones of Punjab, Pakistan [PDF]

open access: yes
The crop protection strategy in Pakistan is almost entirely based on pesticide use whereas development of integrated pest management (IPM) based technologies is in its initial phases of scrutiny as well as implementation. The inefficient use of chemicals
Ahmad, Iftikhar   +3 more
core   +1 more source

Improvement of biological control by volatile plant compounds [PDF]

open access: yes, 2005
Compared to conventional farming the pest management strategies in organic farming is based on better plant resistance and sustainable cultivation technique that does not destroy the natural enemies of pest insects. Methods that reduce feeding efforts of
Holopainen, Jarmo K.
core  

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