Results 81 to 90 of about 1,164,427 (301)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Scientific ReportsUptake of biochar for fuel briquetting and soil amendment is constrained in sub-Saharan Africa by inadequate knowledge of the quantity and distribution of feedstocks. This study assessed the quantities and spatial distribution of crop and forest residues
Timothy Namaswa +8 more
doaj +1 more source
Economics of Biomass Fuels for Electricity Production: A Case Study with Crop Residues [PDF]
In the past, studies on agricultural feedstocks for energy production were motivated by rising fossil fuel prices interpreted by many as caused by resource depletion. However, today's studies are mainly motivated by concerns for climate change and global
McCarl, Bruce A., Maung, Thein A.
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Estimation of N2O emission factors for soils depending on environmental conditions and crop management [PDF]
, 2009 Nitrous oxide (N2O) contributes 8% to anthropogenic global warming, of which about one third are direct emissions of agricultural soils. These N2O emissions are often estimated using the default IPCC 2006 emission factor of 1% of the amount of N applied ...
Velthof, G.L., Lesschen, J.P.
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Alternatives to crop residues for soil amendment
, 1997 Metadata only recordIn semiarid agroecosystems, crop residues can provide important benefits of soil and water conservation, nutrient cycling, and improved subsequent crop yields.
Unger, P. W., Powell, J. M.
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Environmental Factors Affecting the Mineralization of Crop Residues
Agronomy, 2020 The aim of this article is to present the issues related to the significance of microorganisms in the mineralization of crop residues and the influence of environmental factors on the rate of this process.
Aleksandra Grzyb +2 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source