Results 91 to 100 of about 54,953 (261)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Nawożenie słomą i resztkami pożniwnymi międzyplonu wsiewki jako czynnik kształtujący plon i wartość technologiczną buraka cukrowego

open access: yesAgronomy Science, 2004
The field experiments was carried out in the years 1994–1997 at the Agricultural Experimental Stations in Zawady, on cereal-fodder strong soils, in random blocks design in three replications.
Danuta Buraczyńska
doaj  

Evaluating Soil Bacteria for the Development of New Biopreparations with Agricultural Applications

open access: yesApplied Sciences
This study evaluates various strains of soil bacterial for use in the development of new biopreparations. Mesophilic spore-forming bacteria were isolated from cultivated soil and analysed for their enzymatic activity, ability to decompose crop residues ...
Patrycja Rowińska   +7 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Response of Bacterial Community Structure in the Bulk Soil and Rice Straw Residues under Different Crop Rotation Systems

open access: yesAdvances in Agriculture
This study investigated the effect of upland crop rotation on soil bacterial community in bulk soil and rice straw residues in the alluvial soils. Soil samples and rice straw residues in two crop rotation models including triple rice and rice-upland ...
Tran Van Dung   +4 more
doaj   +1 more source

Bioprocessing of Two Crop Residues for Animal Feeding into a High-Yield Lovastatin Feed Supplement. [PDF]

open access: yesAnimals (Basel), 2022
Ábrego-García A   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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