Results 71 to 80 of about 870,191 (308)
College of Agriculture, G. B. Pant University of Agr. and Tech., Pantnagar (Dist.
openaire +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
MT-CYP-Net: Multi-task network for pixel-level crop yield prediction under very few samples
Accurate and fine-grained crop yield prediction plays a crucial role in advancing global agriculture. However, the accuracy of pixel-level yield estimation based on satellite remote sensing data has been constrained by the scarcity of ground truth data ...
Shenzhou Liu +4 more
doaj +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
A better nitrogen use to improve organic wheat production [PDF]
Different crop management strategies are investigated in representative soils and climatic conditions of Denmark to enhance the yield and quality of organic wheat.
Doltra, Jordi
core
The combined effects of cover design parameters on tomato production of a passive greenhouse [PDF]
The objective of this paper is to demonstrate the need of a multiple design parameter approach to greenhouse design. To illustrate this need, we determined the combined effects of cover design parameters on tomato production of a passive greenhouse, that
Gazquez, J.C. +3 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Crop Yield Prediction Using Deep Reinforcement Learning Model for Sustainable Agrarian Applications
Predicting crop yield based on the environmental, soil, water and crop parameters has been a potential research topic. Deep-learning-based models are broadly used to extract significant crop features for prediction. Though these methods could resolve the
Dhivya Elavarasan +1 more
doaj +1 more source
ESTIMATING CORN YIELD RESPONSE MODELS TO PREDICT IMPACTS OF CLIMATE CHANGE [PDF]
Projections of the impacts of climate change on agriculture require flexible and accurate yield response models. Typically, estimated yield response models have used fixed calendar intervals to measure weather variables and omitted observations on solar ...
Dixon, Bruce L. +3 more
core +1 more source
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source

