Results 141 to 150 of about 483,239 (310)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
The long-term agronomic performance of organic stockless rotations [PDF]
, 2002 This report was presented at the UK Organic Research 2002 Conference. Two long-term experiments were established with the aim of evaluating the agronomic and economic performance of organic stockless rotations.
Cormack, William F +2 more
core
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
A COMPARISON OF SUBJECTIVE AND HISTORICAL CROP YIELD PROBABILITY DISTRIBUTIONS [PDF]
Forecast distributions based on historical yields and subjective expectations for 1987 expected crop yields were compared for 90 Western Kentucky grain farms. Different subjective probability elicitation techniques were also compared.
Pease, James W.
core +1 more source
Crop yields in organic and conventional production – studies from the Öjebyn project [PDF]
, 2002 This report was presented at the UK Organic Research 2002 Conference. In order to develop organic dairy production a system study called “The Öjebyn Project” was started in 1990.
Jonsson, Simon
core
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
ALTERNATIVE METHODS OF FORECASTING AGRICULTURAL WATER DEMAND: A CASE STUDY ON THE FLINT RIVER BASIN IN GEORGIA [PDF]
Future agricultural water demands are determined by employing forecasts from irrigated crop acreage models. Forecasts of prices and yields, and variances and covariances of crop returns are employed for forecasting crop acreage.
Banerjee, Swagata (Ban) +3 more
core +1 more source
Winter Canola Planting Date x Seeding Rate Trial [PDF]
, 2014 Because winter canola is a relatively new crop for the Northeastern United States, optimal planting dates for winter canola have not yet been established for this region.
Cummings, Erica +4 more
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source