Results 161 to 170 of about 2,692,904 (342)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
IEEE AccessA worldwide crop loss ranging from approximately 6 to 60% in pearl millet has been reported due to downy mildew caused by Sclerospora graminicola. This disease is transmitted through soil or seeds carrying oospores.
Geeta Rani +4 more
doaj +1 more source
Evaluation of cover crops in high tunnel vegetable rotation [PDF]
, 2013 Organic vegetable production within high tunnels allows for an extended growing season, crop protection, and environmental control. The USDA National Organic Program (NOP) standards mandate evidence that the soil has been maintained and improved over the
Mays, Neal +3 more
core +2 more sources
Breeding crops to feed 10 billion
Nature Biotechnology, 2019 L. Hickey +9 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
An investigation into the relationship between preceding break crops and weed populations in barley crops in organic ley/arable rotations [PDF]
, 2002 This report was presented at the UK Organic Research 2002 Conference. The relationship between weed populations and cereal crops following nine organic break crops was investigated in field trials in Warwickshire, Aberdeenshire and Ceredigion in 2001 ...
Litterick, Audrey M +2 more
core
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Micro-Level Decision for Area Shift in Favour of High-Value Crops: A Case of Horticultural Crops [PDF]
Area shift towards horticultural crops is vital for increasing farm income, productivity and overall employment in the agricultural sector. Several economic (price and income) and non-economic (food-security concerns) factors influence farmers’ decisions
Mehta, Pradeep Kumar
core +1 more source
Optimizing a green manure-based row cropping system for organic cereal production [PDF]
, 2018 A row cropping system with an increase of row distance to 24 cm increased the growth of undersown cover crops and allowed 1-2 passes of interow hoeing for weed control before sowing cover crops.
Phan, Hong TT +1 more
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source