Results 91 to 100 of about 10,673,672 (266)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Examination of the Peripheral Nervous System in Children With Spinal Muscular Atrophy: A High‐Resolution Ultrasonographic Study

Brain and Behavior
Objectives Recent studies have shown that high‐resolution ultrasound (HRUS) devices allow us to accurately measure peripheral nerves in newborns. In consideration of these developments, this study aimed to analyze the structure and cross‐sectional area ...
Janina Wurster, Erin West, Sandro Meier, Noé Phillip Bürke, Lynn Jansen, Philip Julian Broser   +5 more
doaj   +1 more source

Fat beyond muscle: Assessing epimuscular fat of the lumbar spine and its association with vertebral level, demographics, BMI, and low back pain

Brain and Spine
Introduction: Epimuscular fat (EF) has rarely been studied in the context of low back pain (LBP). Research question: This study aims to assess the presence and extent of EF in the lumbar muscles and its association with vertebral level in patients with ...
Jacopo A. Vitale, Anne F. Mannion, Daniel Haschtmann, Mario Ropelato, Tamás F. Fekete, Frank S. Kleinstück, Markus Loibl, Tina Haltiner, Fabio Galbusera   +8 more
doaj   +1 more source

Cross-sectional analysis of long bones in a sample of ancient Egyptians

The Egyptian Journal of Radiology and Nuclear Medicine, 2015
Background: As diaphyseal shape is predominantly influenced by mechanical loading history, long bone cross-sections can be used to access activity patterns. The aim of this study was to evaluate long bone cross-sectional properties in a sample of ancient
Moushira Erfan Zaki, Ayman A. Azab, Walaa Yousef, Eslam Y. Wassal, Hala T. El-Bassyouni   +4 more
doaj   +1 more source

Area-based socioeconomic status and mood disorders: Cross-sectional evidence from a cohort of randomly selected adult women

, 2011
Area-based socioeconomic status and mood disorders: Cross-sectional evidence from a cohort of randomly selected adult ...
MJ Henry (14454321), GC Nicholson (14448297), Julie Pasco (13077054), SL Brennan (14454324), Lana Williams (13082460), Michael Berk (13060851), MA Kotowicz (14448495), Felice Jacka (13069962)   +7 more
core  

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Cross‐sectional area on magnetic resonance images of the semitendinosus tendon is strongly related to the collagen fibril diameter

Journal of Experimental Orthopaedics
Purpose Using a thin semitendinosus tendon as an autograft is a risk factor for poor clinical outcomes after anterior cruciate ligament reconstruction.
Yushin Mizuno, Junsuke Nakase, Tatsuya Ishikawa, Kazuki Asai, Yasushi Takata, Tomoyuki Kanayama, Takuya Sengoku, Noriyuki Ozaki, Hiroyuki Tsuchiya   +8 more
doaj   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Is the Trendelenburg position the only way to better visualize internal jugular veins?

Acta Medica Lituanica, 2019
Background. A larger cross-sectional area (CSA) of the internal jugular vein (IJV) makes catheterization easier and the Trendelenburg position is used to achieve this. Unfortunately, it is not comfortable for conscious patients.
Šarūnas Judickas, Dalia Gineitytė, Greta Kezytė, Ernestas Gaižauskas, Mindaugas Šerpytis, Jūratė Šipylaitė   +5 more
doaj   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source