Results 41 to 50 of about 685,986 (244)

The viral content ratio between abdomen and head is informative of the relative efficiency with which Bemisia tabaci populations transmit begomoviruses. [P.12] [PDF]

, 2015
Begomoviruses (family Geminiviridae) are transmitted by the whitefly Bemisia tabaci in a circulative non propagative manner. B. tabaci is a species complex composed of at least 24 morphocryptic species which differ in host range, insecticide resistance ...
Gargani, Daniel, Granier, Martine, Peterschmitt, Michel, Urbino, Cica   +3 more
core  

Molecular Epidemiology of Ascariasis: A Global Perspective on the Transmission Dynamics of Ascaris in People and Pigs [PDF]

, 2014
Background The roundworm Ascaris lumbricoides infects 0.8 billion people worldwide, and Ascaris suum infects innumerable pigs across the globe. The extent of natural cross-transmission of Ascaris between pig and human hosts in different geographical ...
Bendall, R P, Betson, M, Copenhagen, Deb, R M, Liverpool School of Tropical Medicine, Nejsum, P, Stothard, J R   +6 more
core   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The origin and prevention of pandemics. [PDF]

, 2010
Despite the fact that most emerging diseases stem from the transmission of pathogenic agents from animals to humans, the factors that mediate this process are still ill defined.
Djoko, Cyrille F, Fair, Joseph N, Lebreton, Matthew, Pike, Brian L, Rimoin, Anne W, Saylors, Karen E, Tamoufe, Ubald, Wolfe, Nathan D   +7 more
core   +1 more source

Advances in Bovine Coronavirus Epidemiology

Viruses, 2022
Bovine coronavirus (BCoV) is a causative agent of enteric and respiratory disease in cattle. BCoV has also been reported to cause a variety of animal diseases and is closely related to human coronaviruses, which has attracted extensive attention from ...
Qinghe Zhu, Bin Li, Dongbo Sun
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Origin and cross-species transmission of bat coronaviruses in China. [PDF]

Nat Commun
Bats are presumed reservoirs of diverse coronaviruses (CoVs) including progenitors of Severe Acute Respiratory Syndrome (SARS)-CoV and SARS-CoV-2, the causative agent of COVID-19.
Latinne A, Hu B, Olival KJ, Zhu G, Zhang LB, Li H, Chmura AA, Field HE, Zambrana-Torrelio C, Epstein JH, Li B, Zhang W, Wang LF, Shi ZL, Daszak P.   +14 more
europepmc   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Using host species traits to understand the consequences of resource provisioning for host–parasite interactions [PDF]

, 2017
1.Supplemental food provided to wildlife by human activities can be more abundant and predictable than natural resources, and subsequent changes to wildlife ecology can have profound impacts on host–parasite interactions.
Altizer, Sonia, Becker, Daniel J., Streicker, Daniel G.   +2 more
core   +2 more sources

SARS-CoV-2 outbreak in lions, tigers, and hyenas at Denver Zoo

mSphere
In late 2019, SARS-CoV-2 spilled over from an animal host into humans, where it efficiently spread, resulting in the COVID-19 pandemic. Through both natural and experimental infections, we learned that many animal species are susceptible to SARS-CoV-2 ...
Emily N. Gallichotte, Laura Bashor, Katelyn Erbeck, Lara Croft, Katelyn Stache, Jessica Long, Sue VandeWoude, James C. Johnson, Kristy L. Pabilonia, Gregory D. Ebel   +9 more
doaj   +1 more source