Results 131 to 140 of about 482,387 (295)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Increasing Local Community Resilience in the EU-Ukraine Cross-Border Area

Studia Regionalne i Lokalne
Nowadays, the development of local communities is hindered by crises, external shocks, and disturbance. Under such circumstances, an important characteristic is their resilience, i.e.
Khrystyna Prytula, Ewa Łaźniewska, Anna Maksymenko, Yaroslava Kalat, Olha Demedyuk   +4 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Foreign Bank Penetration and Private Sector Credit in Central and Eastern Europe [PDF]

We analyse foreign bank penetration in Central and Eastern Europe (CEE)and its influence on private sector credit,taking into account both cross-border credit and credit by foreign bank subsidiaries.
Iman van Lelyveld, Ralph de Haas
core  

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

BALANCING THE ECOLOGICAL FOOTPRINT AND SUSTAINABLE TOURISM IN THE LACU SĂRAT AREA, BRĂILA

ACROSS
As a fundamental component in the worldwide evolution of eco-friendly tourism, nature conservation areas play an extremely essential role in community and provincial development.
Camelia Mariana BĂLĂNICĂ DRAGOMIR, Ciprian CUZMIN, Ionel APOSTOLATU   +2 more
doaj  

Association between depressive symptoms and smoking intensity with ethnic minorities in Yunnan Province, China: a moderated mediation model

BMC Psychology
Background Previous research has indicated that depressive symptoms may contribute to an escalation in smoking intensity; however, our knowledge regarding the underlying mediating and moderating mechanisms of this association among ethnic minorities ...
Xinping Wang, Ying Chen, Xuan Wen, Yan Xiao, Xiaoju Li, Jie Chen, Yuan Huang, Rui Deng   +7 more
doaj   +1 more source

Development of a colloidal gold immunochromatographic strip for the rapid detection of fowl adenovirus serotype 4 using prepared penton protein-specific monoclonal antibodies

Frontiers in Veterinary Science
Fowl adenovirus serotype 4 (FAdV-4) is the primary pathogen responsible for hydropericardium-hepatitis syndrome (HHS) and is associated with high mortality rates (20–80%) in 3–6-week-old chickens.
Sisi Luo, Sisi Luo, Bingyi Yang, Jiaoling Huang, You Wei, Zhixun Xie, Xiaofeng Li, Aiqiong Wu, Zhihua Ruan, Sheng Wang, Yanfang Zhang, Meng Li, Liji Xie, Ming Yan, Weiwei Wang, Ping Wei   +15 more
doaj   +1 more source

PERSPECTIVES OF CROSS BORDER COOPERATION OF THE REPUBLIC OF MOLDOVA WITHIN THE FRAMEWORKS OF THE ENPI (2007-2013) [PDF]

This article emphasizes the opportunities of the Republic of Moldova in the domain of cross border cooperation for the timeline that follows the implementation of the Neighborhood Program Romania – Republic of Moldova 2004-2006.
Nicolae Dandis
core  

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source