Results 61 to 70 of about 4,375 (289)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

EUROPEAN CROSS-BORDER MERGERS AND ACQUISITIONS- REALITIES AND PERSPECTIVES [PDF]

This paper analyses the impact of the economic and financial crisis on merger and acquisition activity in Europe and the latest trends manifested on the cross-border merger and acquisition market involving European companies.
Vancea Mariana
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Cross-border mergers and acquisitions and the role of trade costs [PDF]

Cross-border mergers and acquisitions (M&As) have increased dramatically over the last two decades. This paper analyses the role of trade costs in explaining the increase in both the number and the value of cross-border mergers and acquisitions.
Holger G�rg, Miriam Manchin, Alexander Hijzen   +2 more
core  

Global Trends of International Mergers and Acquisitions in the Energy Sector [PDF]

International Economic Policy, 2017
The article explores conditions, factors and results of mergers and acquisitions in international business with the example of the energy industry.
Liubov Galperina, Yuliia Klen
doaj  

Liberalizaiton of Cross-Border Mergers and Acquisitions in Korea: Economic Impacts

East Asian Economic Review, 1997
Most OECD Member countries have made the main part of the world's direct investment - international mergers and acquisitions (M & A) completely liberalized, on the contrary, South Korea still has several limitations to this.
Yunjong Wang
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Cross-Border Mergers and acquisitions: Financial and institutional forces [PDF]

Cross-border mergers and acquisitions (M&As) sharply increased over the last two decades. It is often pointed out that cross-border capital reallocation is partly the result of financial liberalization policies, government policies and regional ...
Coeurdacier, Nicolas, De Santis, Roberto A., Aviat, Antonin   +2 more
core  

Corporate governance, international financial development, and cross-border mergers and acquisitions

International Review of Economics & Finance
This study, based on a dataset of Chinese listed companies from 2003 to 2023, explores the impact of corporate governance, international financial development, and their interactions on enterprises' cross-border mergers and acquisitions (M&A).
Yafei Xing, Junwei Wang, Yitian Lu
doaj   +1 more source

Assortative matching in cross-border mergers and acquisitions

Review of World Economics
Abstract A standard assumption in models of cross-border mergers and acquisitions (M&As) is that highly productive acquirers transfer their productivity level to that of the less productive target. However, our stylized evidence suggests that this is not the case and that the post-merger firm productivity is
Brakman, Steven, Garretsen, Harry, Gerritse, Michiel, van Marrewijk, Charles   +3 more
openaire   +3 more sources