Results 121 to 130 of about 773,156 (307)

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Challenge to SME to Survive in Food Dynamic Markets: Innovation and Efficient Networks [PDF]

The EU food entrepreneurs are facing dramatic changes in the competition arena. Globalization and liberalization processes are offering cheaper food products in international markets, either from countries with better comparative advantages or with more ...
Briz, Julian, de Felipe, Isabel
core   +1 more source

Research on the Cross-Chain Model of Rice Supply Chain Supervision Based on Parallel Blockchain and Smart Contracts. [PDF]

Foods, 2022
Peng X, Zhang X, Wang X, Li H, Xu J, Zhao Z, Wang Y.   +6 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Towards blockchain interoperability: a comprehensive survey on cross-chain solutions

Blockchain: Research and Applications
The rapid expansion of decentralized finance (DeFi) applications has catalyzed the emergence of new blockchain systems at an unprecedented pace. However, these systems are largely evolving in isolation, hindering the development of a cohesive ecosystem ...
Wenqing Li, Zhenguang Liu, Jianhai Chen, Zhe Liu, Qinming He   +4 more
doaj   +1 more source

Structure of the fibrinogen γ‐chain integrin binding and factor XIIIa cross‐linking sites obtained through carrier protein driven crystallization [PDF]

, 1999
Scott Ware, W.F. Anderson, John P. Donahue, Jacek Hawiger   +3 more
openalex   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

A secure dynamic cross-chain decentralized data consistency verification model

Journal of King Saud University: Computer and Information Sciences
The continuous increase in the number of transactions is exerting significant pressure on the storage capacity of blockchains. By storing data on multiple blockchains and interacting with each other with cross-chain technology, the storage pressure can ...
Jiahao Zhao, Yushu Zhang, Jiajia Jiang, Zhongyun Hua, Yong Xiang   +4 more
doaj   +1 more source

Predicting and Comparing the Subjective Health Experience of Older Cancer Survivors and Non‐Cancer Survivors: A Modeling Approach

Aging and Cancer, EarlyView.
This study underscores the significant influence of frailty and vitality on the subjective health experience of older cancer survivors with acceptance and control emerging as salient mediators. These findings affirm the conceptual and empirical robustness of the model highlighting its potential utility in shaping future interventions for older cancer ...
Damien S. E. Broekharst, Sjaak Bloem, Eline J. Mertens, Nathascha Hanzen, Michel van Agthoven   +4 more
wiley   +1 more source

An empirical study on deployment in cross-chain decentralised autonomous organisations

Blockchain: Research and Applications
Decentralised Autonomous Organisations (DAOs) are self-governing democratic entities that operate and provide services via smart contracts on behalf of their users.
Jakob Svennevik Notland, Jingyue Li, Mariusz Nowostawski   +2 more
doaj   +1 more source