Results 141 to 150 of about 7,877,791 (334)

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

open access: yesFEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi   +6 more
wiley   +1 more source

Significant differences in cross cultural negotiations [PDF]

open access: yes
This paper analyses the importance of different factors that influences cross cultural negotiations. Learning about the components of a cross cultural negotiation process to increase negotiators’ success in avoiding barriers and failures in the ...
Luminita Vochita
core  

European American Therapist Self-Disclosure in Cross-Cultural Counseling [PDF]

open access: yes, 2006
Eleven European American psychotherapists\u27 use of self-disclosure in cross-cultural counseling was studied using consensual qualitative research. As reasons for self-disclosing, therapists reported the intent to enhance the counseling relationship ...
Burkard, Alan W.   +4 more
core   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

TRANSGENDER COMMUNITY ACTIVITIES AND THEIR MARRIAGE CONCEPT IN YOGYAKARTA

open access: yesAl-Ahwal: Jurnal Hukum Keluarga Islam, 2016
Transgender have been considered as someone who always marginalized in their life, so they always get moral discrimination, social and even religion.
Muta’Ali Rauf
doaj  

Preparing Teachers for Their Prophetic Role to Serve with Heart, Head, and Hands

open access: yes, 2007
As teacher preparation programs seek to diversify their pre-service teachers’ exposure to teaching situations, Mount Vernon Nazarene University’s Education Department has discovered how to maximize its freshman’s educational technology field experiences ...
Audeoud, Martine, Harvel, Cindy
core  

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Society as a “context” of art production and the phenomenon of feature films citation in connection with the notion of national identity

open access: yesPolylinguality and Transcultural Practices, 2014
The reason for creating any work of art and above all, “secondary reality” of a film is the lack or excess of something in society, the desire of the masses to realize the primary reality and its transformation [1].
E L Koudrjavtseva
doaj  

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

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