Results 191 to 200 of about 1,770,335 (387)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

The Griffiths Development Scales‐Chinese (GDS‐C): A cross‐cultural comparison of developmental trajectories between Chinese and British children

open access: yesChild: Care, Health and Development, 2018
W. Tso   +12 more
semanticscholar   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Media Audiences| The Internet as a Cultural Forum: A European Perspective

open access: yesInternational Journal of Communication, 2015
Jensen and Helles’ model for studying the Internet as a cultural forum describes six prototypical communicative practices based on synchronicity and number of participants.
Galit Nimrod, Hanna Adoni, Hillel Nossek
doaj  

Cross-Cultural Comparison of the Contexts Associated with Emotional Outbursts. [PDF]

open access: yesJ Autism Dev Disord, 2023
Chung JCY   +5 more
europepmc   +1 more source

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