Results 41 to 50 of about 160,702 (264)

Palliative Care in Advanced Dementia: Comparison of Strategies in Three Countries

open access: yesGeriatrics, 2021
Palliative care including hospice care is appropriate for advanced dementia, but policy initiatives and implementation have lagged, while treatment may vary.
Shelley A. Sternberg   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Coercive Therapy in East and West: A Brief Review [PDF]

open access: yesIranian Journal of Psychiatry, 2009
"nAbstract: The physician-patient relationship has been undergoing significant changes in recent decades in Western countries. Taking a client-centered approach, society has given more autonomy and freedom to patients.
Mohammad Jafar Bahredar, Ali Firoozabadi
doaj  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A checklist for translating and adapting questionnaires (CTAQ) in healthcare research: insights from a Delphi method approach

open access: yesTropical Medicine and Health
Purpose Accurate translation and adaptation of survey questionnaires are essential for ensuring validity and reliability in cross-cultural healthcare research.
Nguyen Tran Minh Duc   +29 more
doaj   +1 more source

Cultural Adaptations of Evidence-Based Interventions in Dementia Care: A Critical Review of Literature

open access: yesJournal of Ageing and Longevity
Cultural adaptation is essential for ensuring that interventions are relevant and effective across diverse sociocultural contexts. However, little is known about how these adaptations are conducted and whether they follow structured, evidence-based ...
Michael C. Ibekaku   +4 more
doaj   +1 more source

Measurement of job motivation in TEDS-M: testing for invariance across countries and cultures

open access: yesLarge-scale Assessments in Education, 2016
The paper presents the challenges of cross-country and cross-cultural research on the motivation to become a mathematics teacher based on data from the “Teacher Education and Development Study in Mathematics (TEDS-M)”.
Christin Laschke, Sigrid Blömeke
doaj   +1 more source

Using the Model Statement Technique as a Lie Detection Tool: A Cross-Cultural Comparison [PDF]

open access: yesPsychology in Russia: State of Art, 2019
Background. Researchers have started to demonstrate that verbal cues to deceit can be elicited through specific interview protocols. One that has yielded success is the Model Statement technique, which works as a social comparison and raises interviewees’
Aldert Vrija   +6 more
doaj   +1 more source

Premodern Confederacies: Balancing Strategic Collective Action and Local Autonomy

open access: yesFrontiers in Political Science, 2022
A confederacy is generally understood to be a formal, institutionalized alliance of peoples who act in mutual support to achieve common ends. While the emergence and maintenance of early and pre-modern states have received tremendous scholarly attention ...
Jennifer Birch
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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