Results 61 to 70 of about 902,872 (216)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

One Planet, Many Cultures: Understanding Environmental Responsibility Through Diverse Values

open access: yesAustralian Journal of Environmental Education
The study investigates the interplay between personal values and attitudes toward environmental responsibility (ER) among MBA students from two distinct cultural contexts: Australia (individualist) and India (collectivist).
Asit Bhattacharyya
doaj   +1 more source

Evaluating and Validating Emotion Elicitation Using English and Arabic Movie Clips on a Saudi Sample

open access: yesSensors, 2019
With the advancement of technology in both hardware and software, estimating human affective states has become possible. Currently, movie clips are used as they are a widely-accepted method of eliciting emotions in a replicable way.
Sharifa Alghowinem   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A cross-cultural study on the adoption intention of generative artificial intelligence among international students in China

open access: yesFrontiers in Education
Against the backdrop of the deep integration of higher education internationalization and generative artificial intelligence (GAI), international students in China, as a distinctive cross-cultural group, have not been sufficiently explored regarding the ...
Guijun Fu, Guijun Fu, Kai Cao
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Cross-Cultural Analysis of Consumers’ Avoidance of Snack Food Ingredients Across 13 Countries Using Check-All-That-Apply (CATA) Method

open access: yesFoods
Snack foods are increasingly important because of irregular eating patterns in busy lives. Many consumers state that reading ingredients is important to them making rational choices when consuming snacks.
Yunjeong Cho   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Parents’ Growth Mindsets and Home-Learning Activities: A Cross-Cultural Comparison of Danish and US Parents

open access: yesFrontiers in Psychology, 2020
Mindset is a term commonly used to represent an individual’s beliefs about the role of ability and effort in learning. In this study, we assessed parental mindset—ability mindset and effort mindset—for 497 parents in two countries (United States and ...
Laura M. Justice   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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