Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
Commentary: White matter functional connectome gradient dysfunction in major depressive disorder. [PDF]
Cheng S, Chen B, Lu J.
europepmc +1 more source
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos +2 more
wiley +1 more source
Explainable deep learning for healthcare workforce attrition: a methodological study on the Watson healthcare synthetic benchmark. [PDF]
Yin D, Lu X, Mei T.
europepmc +1 more source
Objective Gastrointestinal (GI) involvement can lead to malnutrition in patients with systemic sclerosis (SSc). Body mass index (BMI) remains the most widely used marker to screen nutritional status. We aimed to identify predictors of lower BMI in patients with SSc. Methods Patients with SSc from a prospective US cohort meeting 2013 American College of
Ali Y. Ayla +8 more
wiley +1 more source
Morphological and functional evaluation of the left ventricle in severe aortic stenosis with afterload mismatch: a South African single-centre, cross-sectional cardiovascular MRI-based study. [PDF]
Rajah MR, Doubell AF, Herbst PG.
europepmc +1 more source
Objective Hydroxychloroquine (HCQ) is the cornerstone of systemic lupus erythematosus (SLE) management with benefits extending beyond SLE control, including protection against atherosclerotic cardiovascular disease (ASCVD). Although HCQ blood levels reflect recent exposure and long‐term intake reflects medication adherence, the impact of longitudinal ...
Shivani Garg +5 more
wiley +1 more source
Mechanical and Energy Absorption Properties of Porous Royal Water Lily Leaf Vein Cross-Sections Under Quasi-Static Axial Loading. [PDF]
Guo Z, Luo S, He X, He Y, Bai C, Wang Z.
europepmc +1 more source
Observer‐Based Adaptive Event‐Triggered Tracking Control for Fuzzy TS Systems With Premise Mismatch
This paper presents an adaptive logistic event‐triggered observer‐based tracking controller for Takagi‐Sugeno fuzzy systems under constrained inputs and network delays. Leveraging a hybrid LMI and Secretary Bird Optimization approach, this strategy significantly minimizes communication overhead and computational burden while ensuring optimal reference ...
Oussama Djadane +3 more
wiley +1 more source
AI-driven vibration-based event classification in railway switches and crossings. [PDF]
Amin MA, Najeh T, Ghoul A.
europepmc +1 more source

