Results 31 to 40 of about 24,795,048 (250)

The Multiple Sclerosis Severity Allele rs10191329A and Cognitive Function: A UK Biobank Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The genome‐wide association study of Multiple Sclerosis severity linked the genetic variant rs10191329A to long‐term disability and implicated brain resilience as a determinant of outcome. We hypothesised that rs10191329A might influence cognition in other neurological diseases and healthy controls.
Ioanna Zimianiti, Sheena Waters, Adil Harroud, Pernilla Stridh, Ruth Dobson, Benjamin M. Jacobs   +5 more
wiley   +1 more source

The Relationship Between Resilience and Mental Health in Chinese College Students: A Longitudinal Cross-Lagged Analysis

Frontiers in Psychology, 2020
The relationship between resilience and mental health was examined in three phases over 4 years in a sample of 314 college students in China. The present study aimed to gain insight into the reciprocal relationship of higher levels of resilience ...
Yin Wu, Yin Wu, Zhi-qin Sang, Xiao-Chi Zhang, Jürgen Margraf   +4 more
doaj   +1 more source

Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin, Tianyuan Yang, Minglei Liu, Haiyang Luo, Jing Yuan, Ke Zhang, Xinsheng Han, Jing Yang, Yuming Xu   +8 more
wiley   +1 more source

Association between Abdominal Obesity, Vitamin D Levels and Frailty in Chinese Elder Adults [PDF]

Zhongguo quanke yixue
Background The incidence of frailty among the elderly in China increases with age, investigating the mechanisms by which central obesity and vitamin D levels contribute to the development of frailty is essential for effective management strategies ...
YIN Dan, HE Huijuan, LI Mengying, WANG Xiangrong, LI Lin
doaj   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Executive dysfunction and impulsivity in adolescence: a cross-lagged panel network analysis

BMC Psychology
Background Based on the perspective of network psychopathology, this study investigates the networks of executive dysfunction and impulsivity in adolescents, with the aim of identifying central and bridge symptoms. Methods This study measured impulsivity
Changsheng Hu, Lingying Jin, Delin Yu, Siyuan Zhang, Zhiyu Lu   +4 more
doaj   +1 more source

Reliability Prediction Based on Multi-State Dynamic Bayesian Network Structure Learning for Complex System With Time-Lagged Correlation

IEEE Access
Due to the complicated interaction in complex systems, correlations between modules are nonlinear and relate to time intervals. In this paper, a novel correlation analysis method based on cross correlation analysis and using two parameter matrixes to ...
Kaixin Liu, Weilu Chen
doaj   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez, Carmen Espejo, Georgina Arrambide, Mireia Castillo, Marta Rodriguez, Helena Ariño, Iker Elosua, Carmen Tur, Angela Vidal‐Jordana, Andreu Vilaseca, Joaquín Castilló, Ingrid Galán, Luciana Midaglia, Carlos Nos, Breogan Rodríguez‐Acevedo, Ana Zabalza, Luca Bollo, Agustín Pappolla, René Carvajal, Neus Mongay‐Ochoa, Jordi Rio, Jaume Sastre‐Garriga, Manuel Comabella, Gesualdina Busiello, Sofia Sceppacuercia, Àlex Rovira, Xavier Montalban, Mar Tintoré, Cristina Auger, Álvaro Cobo‐Calvo   +29 more
wiley   +1 more source

Anxiety and depression as potential risk factors for limited pain management in patients with elderly knee osteoarthritis: a cross-lagged study

BMC Musculoskeletal Disorders
Background Pain management for knee osteoarthritis (KOA) patients is challenging. Pain arises from both physiological and psychological interactions, with anxiety and depression potentially contributing as risk factors that hinder effective pain ...
Wenhao Yang, Guangyuan Ma, Jingchi Li, Taiyuan Guan, Dingchang He, Dujiang Yang, Guoyou Wang, Hui Shi   +7 more
doaj   +1 more source

The bidirectional relationship between emotional distress and subjective wellbeing among college students: a cross-lagged network analysis

Frontiers in Psychology
PurposeThis study examined the bidirectional relationship between subjective wellbeing (SWB) and emotional distress (ED) among college students from a network perspective.
Mengmeng Yuan, Wei Zhou, Bin Chen, Chang Hu, Joston Gary   +4 more
doaj   +1 more source