Results 101 to 110 of about 36,070 (257)

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

open access: yesAdvanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda   +8 more
wiley   +1 more source

The reciprocal relationship between social exclusion and basic psychological needs through cross-lagged analysis

open access: yesScientific Reports
Social exclusion has wide-ranging and detrimental effects. This study recruited 771 Chinese college students (Mage = 19.65 years, SDage = 1.04, 74.19% females). The findings of two cross-lagged panel models, administered at three different points in time,
Shuyue Zhang   +7 more
doaj   +1 more source

Longitudinal reciprocal relationship between media violence exposure and aggression among junior high school students in China: a cross-lagged analysis

open access: yesFrontiers in Psychology
IntroductionIncreasing evidence has shown that media violence exposure can influence individual aggression. However, the question of whether there is a causal relationship between media violence exposure and aggression remains complex and contentious ...
Yifei Dou, Meng Zhang
doaj   +1 more source

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

open access: yesAdvanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears   +5 more
wiley   +1 more source

Bidirectional associations between internet use, social isolation, and loneliness among Chinese middle-aged and older adults: a longitudinal cross-lagged study

open access: yesGuangxi Yike Daxue xuebao
Objective To examine the bidirectional longitudinal associations among internet use, social isolation, and loneliness in Chinese middle-aged and older adults, and to explore potential gender differences in these relationships.
Chao Tang   +5 more
doaj   +1 more source

Tropomyosin 1 Promotes Platelet Adhesion and Clot Contraction Separate from Its Roles in Developmental Hematopoiesis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung   +19 more
wiley   +1 more source

Bidirectional relationship between anemia and cognitive function in middle-aged and older Chinese adults: a longitudinal study

open access: yesScientific Reports
The increasing prevalence of anemia and cognitive decline among middle-aged and older adults poses significant public health challenges. While most studies have examined the impact of anemia on cognition, the potential for a bidirectional relationship ...
Jian Xiong   +4 more
doaj   +1 more source

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