Results 131 to 140 of about 183,904 (311)

Parallel 3D Bioprinting on SLIPS‐Microarrays

Advanced Functional Materials, EarlyView.
This work introduces the first truly parallel 3D bioprinting method, enabling both the simultaneous fabrication of hundreds of cell laden hydrogel 3D structures and their HTS in individual liquid compartments. By integrating Digital Light Processing (DLP) stereolithography with functional micropatterns, the platform decouples printing time from array ...
Julius von Padberg, Julian A. Serna, Maike Schliephake, Pavel A. Levkin   +3 more
wiley   +1 more source

An integrative structural biology approach to identify the binding mode of a nanobody towards the pea ascorbate peroxidase

Computational and Structural Biotechnology Journal
The optimization of diagnostic devices such as biosensors often requires understanding the molecular details of the interaction between capture and target biomolecules. This can be experimentally obtained by cryo-electron microscopy, the preferred method
Claudia D’Ercole, Marco Orlando, Kristina Eleršič Filipič, Ario de Marco   +3 more
doaj   +1 more source

Effect of crosslinker multiplicity on the gel point in ATRP [PDF]

, 2010
Du Prez, Filip, Gao, Haifeng, Matyjaszewski, Krzysztof, Van Camp, Wim   +3 more
core   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

Advanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann, Nicolás Montesdeoca, Johannes Karges   +2 more
wiley   +1 more source

Enzymatic Protein Immobilization for Nanobody Array

Molecules
Antibody arrays play a pivotal role in the detection and quantification of biomolecules, with their effectiveness largely dependent on efficient protein immobilization. Traditional methods often use heterobifunctional cross-linking reagents for attaching
Zhuojian Lu, Rui Ge, Bin Zheng, Peng Zheng   +3 more
doaj   +1 more source

Sample preparation for point of care molecular diagnostics of STIs [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Balachandran, W, Crow, P, Manoharanehru, B, McKay, R   +4 more
core  

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

Advanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo, Mi Jeong Lee, Hyun Wook Kang, Seonhee Byeon, Soo‐Kyoung Choi, Nakwon Choi, Seung‐Woo Cho, Yoonhee Jin   +7 more
wiley   +1 more source

Combined Effects of Humic Acid-Modified Magnetic Biochar and AMF on the Properties of Saline-Alkali Soil and Photosynthetic Parameters of Muskmelon

Shuitu Baochi Xuebao
[Objective] To improve humic acid-modified magnetic biochar (HA-MBC) and explore the combined effects of modified biochar and arbuscular mycorrhizal fungi (AMF) on the properties of saline-alkali soils and the growth of muskmelon.
ZHANG Yating, LOU Xueyi, WU Jiarui, LIU Hongyuan, YE Binyu, XIAO Jiamin, LI Jiameng, MIAO Yining, CHEN Xinyan, LIU Yilin, TAN Yuyu, WANG Zhichao, LIU Peng   +12 more
doaj   +1 more source

Chromatin Preparation and Chromatin Immuno-precipitation from Drosophila Embryos

, 2016
This protocol provides specific details on how to perform Chromatin immunoprecipitation (ChIP) from Drosophila embryos. ChIP allows the matching of proteins or histone modifications to specific genomic regions.
Iovino, N., Latrielle, D., Löser, E.
core   +1 more source

Strategies for Loading and Releasing Peptide Therapeutics in Biodegradable Carriers

Advanced Functional Materials, EarlyView.
A biodegradable carrier‐based peptide delivery system is a powerful treatment platform for diverse diseases, owing to its superior therapeutic efficacy and low toxicity. This review examines the conventional peptide‐loaded carrier fabrication process and its current limitations.
Wookyoung Jang, Ki Wan Bong
wiley   +1 more source