Results 51 to 60 of about 64,836 (247)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Cross-Modal Hashing by l_p-Norm Multiple Subgraph Combination

IEEE Access, 2021
With the explosion of multi-modal Web data, effective and efficient techniques are in urgent need for cross-modal data retrieval with relevant semantics.
Dongxiao Ren, Junwei Huang, Zhonghua Wang, Fang Lu   +3 more
doaj   +1 more source

Strategies in cross-modality matching [PDF]

Perception & Psychophysics, 1982
Subjects were tested on cross-and within-modality matching conditions with either a 5-sec or a 20-sec delay imposed between standard and comparison stimuli. Half the subjects were informed before the trial of what the comparison modality would be, while the others were not. There was a strong effect of instructions on the cross-modality conditions, but
A E, Milewski, J, Iaccino
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

DAMAGE IDENTIFICATION METHOD BASED ON CROSS MODEL CROSS MODAL METHOD AND L₁ REGULARIZATION

Jixie qiangdu, 2023
A damage identification method based on CMCM and L1 regularization is proposed. Firstly, the basic principle of cross modal method and the characteristics of L2 regularization and L1 regularization are introduced.
JIN BangHu, SONG YanPeng, QIU Hu
doaj  

Cross-Modal Multivariate Pattern Analysis [PDF]

Journal of Visualized Experiments, 2011
Multivariate pattern analysis (MVPA) is an increasingly popular method of analyzing functional magnetic resonance imaging (fMRI) data(1-4). Typically, the method is used to identify a subject's perceptual experience from neural activity in certain regions of the brain.
Meyer, Kaspar, Kaplan, Jonas T.
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

DCLMA: Deep correlation learning with multi-modal attention for visual-audio retrieval

Machine Learning with Applications
The cross-modal retrieval task aims to retrieve audio modality information from the database that best matches the visual modality and vice versa. One of the key challenges in this field is the inconsistency of audio and visual features, which increases ...
Jiwei Zhang, Hirotaka Hachiya
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source