Results 41 to 50 of about 407 (177)

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

Advanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin, Emma Perrot, Thibault Dhellemmes, Laura Boi, Daniel De Castro Medeiros, Christelle Glangetas, Sylvie Dumas, Sandra Dovero, Nathalie Biendon, Elodie Ladeveze, Maëlle Hardel, Marc Landry, Erwan Bezard, Jérôme Baufreton, Gilberto Fisone, François Georges   +15 more
wiley   +1 more source

Deep Multi-Level Semantic Hashing for Cross-Modal Retrieval

IEEE Access, 2019
With the rapid growth of multimodal data, the cross-modal search has widely attracted research interests. Due to its efficiency on storage and computing, hashing-based methods are broadly used for large scale cross-modal retrieval.
Zhenyan Ji, Weina Yao, Wei Wei, Houbing Song, Huaiyu Pi   +4 more
doaj   +1 more source

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Hyperledger Fabric for the (digitalized) lifecycle of construction products: Applied review on fastening technology

Civil Engineering Design, Volume 7, Issue 1, Page 9-22, March 2025.
Abstract Blockchain technology is a digital decentralized data ledger recording transactions in an encrypted format. Its implementation can potentially hold significant advantages for the built environment, particularly in manufacturing and building product usage aligned with Building Information Modeling (BIM). This paradigm shift toward decentralized
Aileen Pfeil, Dimosthenis Kifokeris, Panagiotis Spyridis   +2 more
wiley   +1 more source

Automated Profiling of Social Behaviors to Assess the Genetic Basis of Evolution of Aggressive Behaviors in Astyanax mexicanus

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Across the animal kingdom, social behaviors such as aggression are critical for survival and reproductive success. While there is significant variation in social behaviors within and between species, the genetic mechanisms underlying natural variation in social behaviors are poorly understood.
Renee Mapa, Stefan Choy, Solomia Lapko, Allison Kimmel, Isabel Carino‐Bazan, Johanna E. Kowalko   +5 more
wiley   +1 more source

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius, David B. Mark Welch, Holger Herlyn   +2 more
wiley   +1 more source

Cross-Modal Hashing Retrieval Based on Density Clustering

IEEE Access
Cross-modal hashing retrieval methods have attracted much attention for their effectiveness and efficiency. However, most of the existing hashing methods have the problem of how to precisely learn potential correlations between different modalities from ...
Xiaojun Qi, Xianhua Zeng, Hongmei Tang
doaj   +1 more source

TDCMR: Triplet-Based Deep Cross-Modal Retrieval for Geo-Multimedia Data

Applied Sciences, 2021
Mass multimedia data with geographical information (geo-multimedia) are collected and stored on the Internet due to the wide application of location-based services (LBS).
Jiagang Song, Yunwu Lin, Jiayu Song, Weiren Yu, Leyuan Zhang   +4 more
doaj   +1 more source

Heat and Cold Waves in Brazil: An ERA5‐Based Analysis of Trends and Seasonality (1980–2024)

International Journal of Climatology, EarlyView.
This study uses ERA5 reanalysis data to assess changes in extreme heat and cold events across Brazil from 1980 to 2024. Results reveal a sharp increase in heatwave frequency and a general decline in coldwave occurrences, though regional variations are substantial.
Alindomar Lacerda Silva, Scott Sheridan
wiley   +1 more source

Discrete Robust Supervised Hashing for Cross-Modal Retrieval

IEEE Access, 2019
Cross-modal hashing has been studied extensively in the past decades for its significant advantage in computation and storage cost. For heterogeneous data points, the cross-modal hashing aims at learning a sharing Hamming space in where one query from ...
Tao Yao, Zhiwang Zhang, Lianshan Yan, Jun Yue, Qi Tian   +4 more
doaj   +1 more source