The association of ultra-processed food intake on age-related muscle conditions: a systematic review and dose-response meta-analysis with meta-regression. [PDF]
Hojjati Kermani MA+10 more
europepmc +1 more source
In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock+8 more
wiley +1 more source
The effect of tennis on male bone mineral density: A meta-analysis. [PDF]
Huiwen H, Ju H, Dong F, Yan F, Tao W.
europepmc +1 more source
ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li+10 more
wiley +1 more source
Global prevalence of dental caries in the older people, 1991 to 2024: a systematic review and meta-analysis. [PDF]
Almasvandi Y+3 more
europepmc +1 more source
A Validated Model to Predict Severe Weight Loss in Amyotrophic Lateral Sclerosis
ABSTRACT Severe weight loss in amyotrophic lateral sclerosis (ALS) is common, multifactorial, and associated with shortened survival. Using longitudinal weight data from over 6000 patients with ALS across three cohorts, we built an accelerated failure time model to predict the risk of future severe (≥ 10%) weight loss using five single‐timepoint ...
David G. Lester+4 more
wiley +1 more source
Prioritized learning of cross-population neural dynamics. [PDF]
Jha T, Sani OG, Pesaran B, Shanechi MM.
europepmc +1 more source
ABSTRACT Objective Spinal muscular atrophy (SMA) significantly impacts motor function. This study aimed to assess the persistent burden and unmet needs among currently treated patients with SMA and their caregivers. Methods Two complementary web‐based surveys were distributed in August 2024 among patients with SMA and their caregivers.
Julie A. Parsons+8 more
wiley +1 more source
Relationship Between Fear of Missing Out and Social Media Fatigue: Cross-Lagged Panel Design.
Yao X+5 more
europepmc +1 more source
Developmental trajectories of loneliness and social support in older adults: based on the parallel process latent growth curve model. [PDF]
Hu C, Chen Y, Li X, Wang X, Chu J.
europepmc +1 more source