Results 301 to 310 of about 13,066,354 (381)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Reciprocal relationship among perceived sleep quality, smartphone overdependence, and depression in Korean adolescents: a cross-lagged analysis using national big data. [PDF]

Sci Rep
Oh WO, Heo YJ.
europepmc   +1 more source

Comparative Bioavailability of Low-dose Micronized-isotretinoin 16 mg & Conventional Isotretinoin 20 mg Under Fasting Condition in Healthy Adult Male Subjects: A Randomized, Single-dose, Two-way, Cross-over Study (Preprint)

Sumit Madan, Sudershan Kumar, Sachin Mehra, Priyank Shah, Mukesh Gabhane, Shruti Dharmadhikari   +5 more
openalex   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Prevalence of suicidal ideation and suicide attempts among Iranian university students: systematic review and meta-analysis. [PDF]

BJPsych Open
Mahdavinoor SMM, Mollaei A, Mousavi N, Bordbari AH, Dehbozorgi R, Seddigh L.   +5 more
europepmc   +1 more source

Case of a 35‐Year‐Old Man With Pain With Sneezing and Leg Weakness Causing Collapse

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case details a 35‐year‐old man with no past medical history who presents with acute paraparesis and urinary retention in the setting of progressive paresthesias and weakness of his lower and upper extremities over several months. He was found to have longitudinally extensive transverse myelitis involving the cervical to mid‐thoracic cord ...
Joey Hsu, Karen Schoedel, Alan Plotzker, Leana Doherty   +3 more
wiley   +1 more source

Assessing Condition-Specific Adverse Event Profiles of Modafinil for Labelled and Off-Label Uses: A Systematic Review and Meta-Analysis. [PDF]

Basic Clin Pharmacol Toxicol
Jung J, Youm J, Kang J, Kim AY, Suh JK, Kang HY.   +5 more
europepmc   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source

A comprehensive evaluation of MRI-based radiogenomics and prognosis prediction in glioma. [PDF]

Front Oncol
Astaraki M, Lazzeroni M, Toma-Dasu I.
europepmc   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source