Results 31 to 40 of about 13,066,354 (381)

Spironolactone in pulmonary arterial hypertension: results of a cross‐over study [PDF]

open access: yesPulmonary Circulation, 2020
The renin–angiotensin–aldosterone system is implicated in the pathophysiology of pulmonary arterial hypertension. We undertook this study to determine the effects of spironolactone, a mineralocorticoid receptor blocker, on collagen metabolism in pulmonary arterial hypertension patients.
Zeenat Safdar   +5 more
openaire   +4 more sources

Pharmacokinetic boosting of olaparib: A randomised, cross-over study (PROACTIVE-study) [PDF]

open access: yesEuropean Journal of Cancer, 2023
Pharmacokinetic (PK) boosting is the intentional use of a drug-drug interaction to enhance systemic drug exposure. PK boosting of olaparib, a CYP3A-substrate, has the potential to reduce PK variability and financial burden. The aim of this study was to investigate equivalence of a boosted, reduced dose of olaparib compared to the non-boosted standard ...
Overbeek, Joanneke K.   +13 more
openaire   +4 more sources

Alcohol and risk of admission to hospital for unintentional cutting or piercing injuries at home: a population-based case-crossover study

open access: yesBMC Public Health, 2011
Background Cutting and piercing injuries are among the leading causes of unintentional injury morbidity in developed countries. In New Zealand, cutting and piercing are second only to falls as the most frequent cause of unintentional home injuries ...
Thornley Simon   +5 more
doaj   +1 more source

Differential mortality and wealth accumulation [PDF]

open access: yes, 1995
The issue of asset accumulation and decumulation is central to the life cycle theory of consumer behavior and to many policy questions. One of the main implications of the life cycle model is that assets are decumulated in the last part of life.
Attanasio, O., Hoynes, H.W.
core   +1 more source

Analysis of the velocity distribution in different types of ventilation system ducts [PDF]

open access: yesEPJ Web of Conferences, 2018
The paper presents the results obtained during the preliminary studies of circular and rectangular ducts before testing the properties elements (elbows, tees, etc.)of rectangular with rounded corners ducts.
Peszyński Kazimierz   +3 more
doaj   +2 more sources

Ferromagnetic to spin glass cross over in (La,Tb)_{2/3}Ca_{1/3}MnO_{3}

open access: yes, 2008
In the series La_{2/3-x}Tb_{x}Ca_{1/3}MnO_{3}, it is known that the compositions are ferromagnetic for smaller values of x and show spin glass characteristics at larger values of x.
Alonso   +21 more
core   +1 more source

Monte-Carlo simulations of photohadronic processes in astrophysics [PDF]

open access: yes, 1999
A new Monte Carlo program for photohadronic interactions of relativistic nucleons with an ambient photon radiation field is presented. The event generator is designed to fulfil typical astrophysical requirements, but can also be used for radiation and ...
Engel, Ralph   +4 more
core   +3 more sources

The Analgesic Effect of Oxytocin in Humans: A Double‐Blind, Placebo‐Controlled Cross‐Over Study Using Laser‐Evoked Potentials

open access: yesJournal of neuroendocrinology, 2016
Oxytocin is a neuropeptide regulating social‐affiliative and reproductive behaviour in mammals. Despite robust preclinical evidence for the antinociceptive effects and mechanisms of action of exogenous oxytocin, human studies have produced mixed results ...
Y. Paloyelis   +5 more
semanticscholar   +1 more source

Legitimation, institutions and regional path creation: a cross-national study of offshore wind

open access: yesRegional studies, 2021
This paper assesses legitimation as a crucial dimension of industry emergence, addressing the neglect of institutional and political aspects of path creation in economic geography.
D. Mackinnon   +5 more
semanticscholar   +1 more source

Single tooth anesthesia versus conventional anesthesia: a cross-over study [PDF]

open access: yesClinical Oral Investigations, 2018
The aim of the present study was to compare an electronic device, the Wand Injection System (Milestone Scientific Livingstone), with conventional anesthesia in terms of the following: pain sensation during anesthetic injection; effectiveness in achieving adequate anesthesia for a complete painless dental treatment; post-operative discomfort; and ...
Campanella, Vincenzo   +7 more
openaire   +5 more sources

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