Results 41 to 50 of about 16,855 (254)

A Comparative Study to Benchmark Cross-Project Defect Prediction Approaches

IEEE Transactions on Software Engineering, 2018
Cross-Project Defect Prediction (CPDP) as a means to focus quality assurance of software projects was under heavy investigation in recent years. However, within the current state-of-the-art it is unclear which of the many proposals performs best due to a lack of replication of results and diverse experiment setups that utilize different performance ...
Steffen Herbold, Alexander Trautsch, Jens Grabowski   +2 more
openaire   +3 more sources

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Cross–Project Defect Prediction With Respect To Code Ownership Model: An Empirical Study

e-Informatica Software Engineering Journal, 2015
The paper presents an analysis of 83 versions of industrial, open-source and academic projects. We have empirically evaluated whether those project types constitute separate classes of projects with regard to defect prediction.
Marian Jureczko, Lech Madeyski
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

Assessing the impact of crucial feature sets in cross-project for defect prediction employing a hybrid feature selection method

Journal of Intelligent Systems
Cross-project defect prediction is an important method of identifying defects in a project. We extract knowledge from the source project and apply it to predict labels for the target project in cross-project defect prediction.
Gul Sana, Faiz Rizwan Bin, Aljaidi Mohammad, Alshammari Muteb   +3 more
doaj   +1 more source

A cross‐project defect prediction method based on multi‐adaptation and nuclear norm

IET Software, 2022
Cross‐project defect prediction (CPDP) is an important research direction in software defect prediction. Traditional CPDP methods based on hand‐crafted features ignore the semantic information in the source code.
Qingan Huang, Le Ma, Siyu Jiang, Guobin Wu, Hengjie Song, Libiao Jiang, Chunyun Zheng   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Interpretable Software Defect Prediction from Project Effort and Static Code Metrics

Computers
Software defect prediction models enable test managers to predict defect-prone modules and assist with delivering quality products. A test manager would be willing to identify the attributes that can influence defect prediction and should be able to ...
Susmita Haldar, Luiz Fernando Capretz
doaj   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source