Results 131 to 140 of about 6,077,443 (312)
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Wally and the Major, tenth edition [picture] /
, 1940 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Wally and the Major, Tenth edition, By Stan Cross, 1/-"--In ink. "Stan Cross"--In pencil, lower right; "page 6"--In pencil, on note attached to verso.; Also available in ...
Cross, Stan, 1888-1977.
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
A bomb from Australia [picture] /
, 1917 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross Feb 18th 1917"--In ink, lower left. "A Bomb From Australia"--In ink, upper margin; "Stan Cross 94 Aberdeen St Perth"--In pencil, on verso.; Also available in an
Cross, Stan, 1888-1977.
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Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
, 1900 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; "Stan Cross"--In ink, lower right. "Reduction No. 1 on 4418 sh[?]"--In pencil, upper left; "sheet 4"--In ink, upper right corner; "Stan Cross 39 Wallaroy Rd Woollahra"--In ink, lower ...
Cross, Stan, 1888-1977.
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
, 1910 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--in ink, lower right. "Stan Cross"--in ink, lower right.
Cross, Stan, 1888-1977.
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Young woman removing military jacket to reveal a bathing suit [picture] /
, 1914 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--In ink, lower left. "Stanley Cross 94 Aberdeen St Perth.
Cross, Stan, 1888-1977.
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