Results 121 to 130 of about 8,215,454 (316)
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Transgenic Cross-Referencing of Inhibitory and Excitatory Interneuron Populations to Dissect Neuronal Heterogeneity in the Dorsal Horn. [PDF]
Front Mol Neurosci, 2020 Browne TJ +7 more
europepmc +1 more source
Genome mapping of tetraploid cotton : towards a saturated and unified map [PDF]
, 2004 DNA-based genetic maps have been produced in nearly all major crop species, thus facilitating the analysis of genome structure and evolution, and improving efficiency and accuracy of breeding.
Bojinov, B. +4 more
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Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Global cross-database search system for X-ray absorption spectra
Journal of Synchrotron RadiationWhile the importance of a systematic overview of scientific data and demands toward data integration are increasing, data capitalization and confidentiality are also emerging competitively.
Masashi Ishii +5 more
doaj +1 more source
Identifiers.org / MIRIAM Registry: annotation and cross-referencing framework
, 2014 This poster was presented at COMBINE 2012 (http://co.mbine.org/events/COMBINE_2012). Abstract We describe our work to provide the community with directly resolvable URIs through Identi ers.org, using information stored in the MIRIAM Registry. Identi ers.org o ffers an annotation and cross-referencing framework which provides perennial, unambiguous and ...
Laibe, Camille, Juty, Navtej
openaire +1 more source
Molecular Oncology, EarlyView.Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
UK Research Information Shared Service (UKRISS) Final Report, July 2014 [PDF]
, 2014 The reporting of research information is a complex and expensive activity for research organisations (ROs). There is little alignment between funders of the reporting requests made to institutions and requests made to individual researchers about their ...
Gartner, R +9 more
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