Results 91 to 100 of about 17,263,696 (263)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
On The Lash Bar Count Algorithm Based on Image Recognition
ITM Web of Conferences, 2016 This paper solved the problem that lash bars were difficult to be quickly and accurately counted,and proposed a kind of lash bar count algorithm based on image recognition through observation and study of the morphology of lash bars, namely the algorithm
Chen Pan-Pan +2 more
doaj +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Marine Radar Target Ship Echo Generation Algorithm and Simulation Based on Radar Cross-Section
Journal of Marine Science and EngineeringIn this study, a simplified radar echo signal model suitable for radar simulators and a Radar Cross-Section (RCS) calculation model based on the Physical Optics (PO) method was developed.
Chang Li +4 more
doaj +1 more source
Experimental Research of Cavitation in Channels of Very Small Scales [PDF]
Transactions of the VŠB-Technical University of Ostrava, Mechanical Series, 2010 This paper deals with defining of experimental methods and with description of an experimental setup used in research of fluid flows in jets and other orifices of very small scales. The jet used in the experiments has an axissymetric shape with circular
Róbert OLŠIAK, Marek MLKVIK
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Painting smock belonging to Stan Cross [realia] /
, 1920 Title devised by cataloguer based on information from acquisition documentation.; Condition: Foxing, discolouration and stains.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic-vn4461057.
Cross, Stan, 1888-1977.
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The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Hydrogen Scattering Correction Method for Neutron Imaging
Yuanzineng kexue jishuNeutron imaging can nondestructively detect the composition and structure of a sample, and has been used in many fields for quantitative analysis. Neutron imaging can be used to detect elements that are difficult to detect with X-rays, such as hydrogen.
YOU Shaochu, HE Linfeng, WU Meimei, LI Zhengyao, RUAN Shihao, WANG Tianyun, CHEN Dongfeng
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Things that make Stan cross [picture] : contending with the county council /
, 1900 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; "Stan Cross"--In ink, lower right. "Page 5"--In ink, on note attached to verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at: http://nla ...
Cross, Stan, 1888-1977.
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