Results 61 to 70 of about 35,590,510 (299)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Cross-sectional area and ratio of the cross-sectional area.

open access: yes, 2022
Cross-sectional area and ratio of the cross-sectional area.
Takashi Ono (520294)   +8 more
core   +1 more source

Cross family christmas card, 1957 [picture] : "greetings at christmas 1957 From stan and jess cross and stephen" /

open access: yes, 1957
Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Copy of original drawing. "Greetings at Christmas 1957 From Stan and Jess Cross and Stephen"; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core   +2 more sources

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Prevalence of obesity and overweight in primary school girls in Tehran, Iran

open access: yesPayesh, 2002
Objective(s):  The rising trends of obesity in children are reflected in increased adult obesity and related morbidity. So we studied the prevalence of obesity in children and the related factors in Tehran.
Mozafary H, Nabaie B
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Panel Unit Root Tests in the Presence of Cross-Sectional Dependency and Heterogeneity [PDF]

open access: yes
An IV approach, using as instruments nonlinear transformations of the lagged levels, is explored to test for unit roots in panels with general dependency and heterogeneity across cross-sectional units.
Wonho Song, Yoosoon Chang
core  

A cross‐sectional study exploring cognitive impairment in kidney failure

open access: yes, 2021
Background: Little is known of the prevalence or associated factors of cognitive impairment in people with kidney failure. Assessment of cognition is necessary to inform comprehension of healthcare information, aptitude for dialysis modality and informed
Theresa Green   +7 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cross-Sectional and Longitudinal Designs

open access: yes, 2012
This presentation looks in-depth at cross-sectional and longitudinal designs. It also looks at the problem of establishing causality (rather than correlation) in social science and uses a video from GapMinder to show the power of temporal data.
Dr Luke Sloan
core  

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