Results 101 to 110 of about 1,045,991 (296)

Breaking Barriers to an AIDS Model with Macaque-Tropic HIV-1 Derivatives

open access: yesBiology, 2012
The development of an animal model of human immunodeficiency virus type 1 (HIV-1)/AIDS that is suitable for preclinical testing of antiretroviral therapy, vaccines, curative strategies, and studies of pathogenesis has been hampered by the human-specific ...
Jason T. Kimata   +2 more
doaj   +1 more source

Cross species transmission of Mycobacterium bovis infection at the wildlife/livestock interface in South Africa [PDF]

open access: yes, 2019
Bovine tuberculosis affects cattle in South Africa and is known to be endemic in wildlife with the African buffalo (Syncerus caffer) being recognized as the maintenance host.
Etter, Eric   +2 more
core  

Interactive rhythms across species: The evolutionary biology of animal chorusing and turn-taking

open access: yes, 2019
The study of human language is progressively moving toward comparative and interactive frameworks, extending the concept of turn‐taking to animal communication.
Greenfield, M., Ravignani, A., Verga, L.
core   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

open access: yesFEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Development of novel, cross-species microsatellite markers for Acropora corals using next-generation sequencing technology

open access: yesFrontiers in Marine Science, 2014
The genus Acropora (Scleractinia, Acroporidae) is one of the most widespread coral genera, comprising the largest number of extant species among scleractinian (reef-building) corals. Molecular phylogenetic studies have suggested that A.
Chuya eShinzato   +6 more
doaj   +1 more source

A new group of hepadnaviruses naturally infecting Orangutans (Pongo pygmaeus) [PDF]

open access: yes, 1999
A high prevalence (42.6%) of hepatitis B virus (HBV) infection was suspected in 195 formerly captive orangutans due to a large number of serum samples which cross-reacted with human HBV antigens.
Heeney, J.L.   +4 more
core   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

open access: yesFEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti   +3 more
wiley   +1 more source

Using genomic DNA-based probe-selection to improve the sensitivity of high-density oligonucleotide arrays when applied to heterologous species

open access: yesPlant Methods, 2005
High-density oligonucleotide (oligo) arrays are a powerful tool for transcript profiling. Arrays based on GeneChip® technology are amongst the most widely used, although GeneChip® arrays are currently available for only a small number of plant and animal
Townsend Henrik J   +7 more
doaj   +1 more source

Cross-species mind-reading

open access: yesAnimal Sentience, 2016
We can never be sure anyone else is sentient. But we can be sure enough in the case of other people, nonhuman primates, mammals, birds, fish, lower vertebrates and invertebrates as to make scepticism academic and otiose (not to mention monumentally cruel). The only genuinely uncertain kinds of cases are jellyfish, microbes and plants.
openaire   +2 more sources

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

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