Results 171 to 180 of about 9,311,801 (213)
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Cross-Species Comparisons of Welfare
2017In her chapter, Tatjana Visak notes that the question of how to do Cross-Species Comparisons of welfare (CSCs) is practically relevant on the assumption that the effects of our (possible) actions on welfare are relevant for what we have reason to do.
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Cross-species comparisons of the pharmacokinetics of ibudilast
Xenobiotica, 2009To enable clinical development of ibudilast for new indications, its pharmacokinetics were characterized in mice, rats, rabbits, dogs, cynomolgus monkeys, and minipigs. Animal pharmacokinetics were compared with a separate study in healthy volunteers. Following oral dosing, the dose-normalized area under the curve (AUC) (DN-AUC(24h)) in humans is 896 ((
L M, Sanftner +5 more
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Cross-Species Homology of the CLN3 Gene
Neuropediatrics, 1997A murine cDNA clone was isolated by screening a mouse cDNA library with the human CLN3 cDNA. Sequence analysis indicates that the corresponding CLN3 proteins are highly homologous. We have compared these with recently identified CLN3 sequences from the dog, the nematode C. elegans, and baker's yeast S. cerevisiae.
P E, Taschner, N, de Vos, M H, Breuning
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Cross-species studies for target validation
Briefings in Functional Genomics and Proteomics, 2002The completion of the genome sequences of several model organisms and the recent development of high throughput procedures to map genes, expression patterns and interactions is providing a steadily increasing number of candidate target genes. The function of most of these genes still remains unknown.
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Cross-Species Studies of Glycolytic Function
1999Researchers probing the functional properties of glycogen (glucose) fermentation to lactate typically work within either one of two theoretical frameworks or models. The first assumes that the cell is analogous to a watery bag of enzymes, while the second assumes that three dimensional order and structure constrain the behaviors of glycolytic ...
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Cross-species network and transcript transfer
2016Metabolic processes, signal transduction, gene regulation, as well as gene and protein expression are largely controlled by biological networks. High-throughput experiments allow the measurement of a wide range of cellular states and interactions. However, networks are often not known in detail for specific biological systems and conditions.
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Ciba Foundation symposium, 1998
Cognitive and neural adaptations in animals have been analysed using the comparative method. Comparisons between closely related species that differ in a cognitive or neural character, and comparison between distantly related species that share a cognitive or neural character, can be used to identify adaptations. Recent research has identified adaptive
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Cognitive and neural adaptations in animals have been analysed using the comparative method. Comparisons between closely related species that differ in a cognitive or neural character, and comparison between distantly related species that share a cognitive or neural character, can be used to identify adaptations. Recent research has identified adaptive
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Where Is Cingulate Cortex? A Cross-Species View
Trends in Neurosciences, 2020Rogier B Mars +2 more
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Cross-Species Tropism and Antigenic Landscapes of Circulating SARS-CoV-2 Variants
Cell Reports, 2022Quan Yuan, Guan Yi, Min Wei
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