Results 61 to 70 of about 9,865,369 (270)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Characterization of Cross-Species Transmission of Drosophila melanogaster Nora Virus
Life, 2022 Drosophila melanogaster Nora virus (DmNV) is a novel picorna-like virus first characterized in 2006. Since then, Nora virus has been detected in several non-Drosophila species, including insects in the Orders Hymenoptera, Lepidoptera, Coleoptera, and Orthoptera.
Ella G. Buhlke +6 more
openaire +3 more sources
Implications of viral transmitted/founder (T/F) dynamics on vaccine development
Human Vaccines & Immunotherapeutics, 2021 Viral infection typically originates from a limited number of virions known as transmitted/founder (T/F) viruses. Studies of cross-species transmission, and intra-species transmission of antigenically variable viruses, indicates T/F variants may express ...
Alexander I. Mosa
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Frequent Cross-Species Transmission of Parvoviruses among Diverse Carnivore Hosts [PDF]
, 2012 Although parvoviruses are commonly described in domestic carnivores, little is known about their biodiversity in nondomestic species. A phylogenetic analysis of VP2 gene sequences from puma, coyote, gray wolf, bobcat, raccoon, and striped skunk revealed ...
Brown, Justin D. +8 more
core
Comparative Genomics of Zoonotic Pathogens: Genetic Determinants of Host Switching and Cross-Species Transmission [PDF]
Emerging infectious diseases of animals that spread to humans (zoonoses) continue to represent a major threat to public health throughout the world. Knowledge of genetic elements that enable pathogens to navigate host shifts and species jumps is crucial ...
Quadri N. Okiki +9 more
core +2 more sources
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Frontiers in MicrobiologyRabies, caused by viruses of the genus Lyssavirus (family Rhabdoviridae), remains a persistent public health and veterinary challenge in Israel, a small but strategically positioned country at the crossroads of Africa, Asia, and Europe.
Maya Weinberg +9 more
doaj +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source