Results 121 to 130 of about 3,494,819 (252)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Portrait of Jessie Cross, Stan's wife, ca. 1920 [picture] /
, 1920 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Jessie Cross Stan's wife"--In ink, on verso.; Also available in an electronic version via the internet at: http://nla.gov.au/nla.pic ...
Cross, Stan, 1888-1977.
core
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Things that make Stan cross [picture] : what makes inflation? /
, 1900 Part of the Stan Cross Archive of cartoons and drawings, 1912-1974.; Inscription: "Stan Cross"--In ink, lower right. "Page 5"--In ink, on note attached to verso.; Title devised by cataloguer.; Also available in an electronic version via the internet at ...
Cross, Stan, 1888-1977.
core
Geo-spatial Information ScienceAccurate estimation of forest aboveground biomass is essential for the assessment of regional carbon cycle and the climate change in the terrestrial ecosystem.
Hungil Jin +4 more
doaj +1 more source
Multiple-source cross-validation
, 2013 Cross-validation is an essential tool in machine learning and statistics. The typical procedure, in which data points are randomly assigned to one of the test sets, makes an implicit assumption that the data are exchangeable. A common case in which this does not hold is when the data come from multiple sources, in the sense used in transfer learning ...
Geras, Krzysztof, Sutton, Charles
openaire +3 more sources
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Parametric and nonparametric bootstrap: an analysis of indoor air data from Kuwait
Kuwait Journal of Science, 2018 This paper discusses the performance of parametric and nonparametric bootstrap for confidence interval (CI) estimation applied to fine particulate matter (PM2.5) data.
Sana BuHamra +2 more
doaj
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source