Results 91 to 100 of about 1,594,443 (315)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Cross-correlation matrices of the functional residues.

open access: yes, 2018
(A) Phosphoribosylanthranilate isomerase, (B) cyclophilin, (C) sialidase and, (D) hexokinase-1. The first row represents the matrices for multi-domain proteins, the second row represents the matrices for single-domain and, the last row represents the ...
Alexandre G. de Brevern (120350)   +2 more
core   +1 more source

Cross-correlation of home range lengths and the number of infected people.

open access: yes, 2022
CCC Total Travel Distance is HR-length (Total Travel Distance). CCC Farthest Distance is HR-length (Farthest Distance). In cross-correlation, the lag was set to eight weeks.
Atsushi Takizawa (13569719)   +1 more
core   +1 more source

Assessment of the Kinetic Trajectory of the Median Nerve in the Wrist by High-Frequency Ultrasound

open access: yesSensors, 2014
Carpal tunnel syndrome (CTS) is typically diagnosed by physical examination or nerve conduction measurements. With these diagnostics however it is difficult to obtain anatomical information in the carpal tunnel.
Yi-Hsun Lin   +3 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Cross-correlation image analysis for real-time particle tracking

open access: yes, 2023
Accurately measuring translations between images is essential in many fields, including biology, medicine, geography, and physics. Existing methods, including the popular FFT-based cross-correlation, are not suitable for real-time analysis, which is ...
Zachariah B. Etienne (17180920)   +8 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Non-Intrusive Impedance Cross-Correlation (ICC) Flow Meter for Dispersed Phase Velocity and Volume Fraction Profile Measurement in Two Phase Flows

open access: yes, 2012
This paper describes the design and implementation of an impedance cross correlation flow meter which can be used in solids-water pipe flows to measure the local solids volume fraction distribution and the local solids velocity distribution.
Lucas, Gary, Muhamedsalih, Yousif
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

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