Results 141 to 150 of about 1,594,443 (315)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

EFFECTS OF DAYLENGTH AND SOIL HUMIDITY ON THE FLOWERING OF COFFEE COFFEA ARABICA L. IN COLOMBIA EFECTO DE LA DURACIÓN DEL DÍA Y LA HUMEDAD DEL SUELO SOBRE LA FLORACIÓN DEL CAFETO COFFEA ARABICA L. EN COLOMBIA

open access: yesRevista Facultad Nacional de Agronomía Medellín, 2011
Coffee flowering data were analyzed in order to explore the effect of two environmental variables that have been considered relevant for this process.
Andrés Javier Peña Quiñones   +4 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

A Multiphase Flow Measurement System Comprising an Impedance Cross Correlation (ICC) Device and an Imaging Electromagnetic Flow Meter (IEF).

open access: yes, 2012
Flow measurements are playing increasingly important roles in many different application areas, such as manufacturing processes and the oil & gas industry.
Meng, Yiqing, Lucas, Gary
core  

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Factor Residuals in SUR Regressions: Estimating Panels Allowing for Cross Sectional Correlation [PDF]

open access: yes
This paper describes a method for estimating panels by imposing a factor structure on the residuals. The method allows SUR estimation of panel models by providing a full-rank estimator of the system covariance matrix when the usual estimate is rank ...
Donald Robertson, James Symons
core  

Contactless Measurement of Pulse Transit Time Between Upper Extremities During Simulated Stenosis

open access: yesCurrent Directions in Biomedical Engineering
This paper proposes a novel approach for the noninvasive assessment of different degrees of stenosis by remote photoplethysmography (rPPG) using an RGB camera.
Tauber Samuel   +3 more
doaj   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Cross-Correlation Based Efficient Technique For Vehicle Occupancy Detection using Magnetoresistive Sensors

open access: yes, 2018
An efficient method to determine the occupancy state of a parking lot by determining the arrival and departure of vehicles from the perturbations in the magnetic field, is proposed. The method is based on cross-correlation of the magnetic field data with
Woei Seng How (10759086)   +7 more
core   +1 more source

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