Results 51 to 60 of about 935,295 (306)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Auto-Correlation Functions of Chaotic Binary Sequences Obtained by Alternating Two Binary Functions

open access: yesDynamics
This paper discusses the auto-correlation functions of chaotic binary sequences obtained by a one-dimensional chaotic map and two binary functions. The two binary functions are alternately used to obtain a binary sequence from a chaotic real-valued ...
Akio Tsuneda
doaj   +1 more source

IM session identification by outlier detection in cross-correlation functions [PDF]

open access: yes2015 49th Annual Conference on Information Sciences and Systems (CISS), 2015
The identification of encrypted Instant Messaging (IM) channels between users is made difficult by the presence of variable and high levels of uncorrelated background traffic. In this paper, we propose a novel Cross-correlation Outlier Detector (CCOD) to identify communicating end-users in a large group of users.
Saad Saleh   +4 more
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Current observations from a looking down vertical V-ADCP: interaction with winds and tide? The case of Giglio Island (Tyrrhenian Sea, Italy)

open access: yesOceanologia, 2017
In the context of the environmental monitoring of the Concordia wreck removal project, measurements of currents, winds and sea level height were made along the eastern coast of the Giglio Island, Tyrrhenian Sea (Italy), during 2012–2013.
Laura Cutroneo   +5 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Measurement of the dipole in the cross-correlation function of galaxies [PDF]

open access: yesJournal of Cosmology and Astroparticle Physics, 2017
It is usually assumed that in the linear regime the two-point correlation function of galaxies contains only a monopole, quadrupole and hexadecapole. Looking at cross-correlations between different populations of galaxies, this turns out not to be the case.
Gaztanaga, Enrique   +2 more
openaire   +2 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Systematic Identification of Average ASR Successful Telecommunications Conversations Using the Concept of Dynamic Systems [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2011
Some industrial, social, and managerial issues have their own intricacies and cannot be solved by simple vision and management hypotheses. Dynamic systems thinking is a way of modeling and analyzing the factors of a system and ultimately finding the ...
Nezamodin Faghih, Mohammad Ghafournian
doaj  

Cross-Correlation Function for Accurate Reconstruction of Heterogeneous Media

open access: yesPhysical Review Letters, 2013
Porous media, heterogeneous materials, and biological tissues are examples of ubiquitous disordered systems, the understanding of which and any physical phenomenon in them entails having an accurate model. We show that a new reconstruction method based on a cross-correlation function and a one-dimensional raster path provides an accurate description of
Pejman, Tahmasebi, Muhammad, Sahimi
openaire   +3 more sources

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