Results 31 to 40 of about 1,030,546 (307)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Constrained pattern of viral evolution in acute and early HCV infection limits viral plasticity

, 2011
Cellular immune responses during acute Hepatitis C virus (HCV) and HIV infection are a known correlate of infection outcome. Viral adaptation to these responses via mutation(s) within CD8+ T-cell epitopes allows these viruses to subvert host immune ...
Paul Klenerman, Malte Heeg, John, Mina, Pfafferott, K, James, Ian, Ulsenheimer, Axel, Helmut M. Diepolder, Lucas, A.D., Silvana Gaudieri, Heeg, M, Rauch, A, Ian James, John, M., Andri Rauch, Klenerman, P., James, I, Simon Mallal, Diepolder, HM, Heeg, Malte, John, M, Mallal, Simon, Lucas, Andrew, Nolan, D., Lucas, M., Heeg, M., Michaela Lucas, Diepolder, H.M., Mallal, S., Gaudieri, S, Lucas, M, Gaudieri, S., Nolan, David, Ulsenheimer, A, Lucas, A, David Nolan, Klenerman, Paul, Diepolder, Helmut M., Pfafferott, K., Klenerman, P, Rauch, A., Ulsenheimer, A., Pfafferott, Katja, Lucas, Michaela, Katja Pfafferott, Andrew Lucas, Rauch, Andri, Diepolder, Helmut M, Axel Ulsenheimer, Mina John, Helmut M Diepolder, Nolan, D, Mallal, S, James, I., Gaudieri, Silvana   +53 more
core   +1 more source

A multispecies model for the transmission and control of mastitis in dairy cows [PDF]

, 2001
Mastitis in dairy cows is a significant economic and animal welfare issue in the dairy industry. The bacterial pathogens responsible for infection of the mammary gland may be split into two main categories: major and minor pathogens. Infection with major
Schukken, Y. H., White, Lisa, Schukken, YH, Medley, GF, White, L. J., Chappell, M. J. (Michael J.), Medley, Graham, Lam, TJ, Lam, T. J. G. M., White, LJ, Chappell, MJ   +10 more
core   +1 more source

Clonality pattern assessed by ERIC-PCR and REP-PCR in extended-spectrum betalactamase- producing Escherichia coli and Klebsiella pneumoniae isolates from patients with nosocomial urinary tract infections. Hospital Regional Lambayeque, Peru

Horizonte Médico, 2018
Objective: To determine the clonality pattern assessed by ERIC-PCR and REP-PCR in extended-spectrum beta-lactamase (ESBL)-producing Escherichia coli and Klebsiella pneumoniae isolates from patients with urinary tract infections at the Hospital Regional
Kelly Lelia López-Ramírez, Kevin Colbert Díaz-Maldonado, Martha Arminda Vergara Espinoza, Olivia Santamaría- Veliz, Luis Miguel Serquén-López, Bustamante Canelo Olinda, Franco Ernesto León-Jimenez, Franklin-Rómulo Aguilar-Gamboa   +7 more
doaj   +1 more source

Risk factors for central venous catheter-related bloodstream infection in oncology patients: an integrative review

Brazilian Journal of Oncology, 2022
The aim of this integrative review was to identify scientific studies on risk factors for bloodstream infections associated with central venous catheters (CVC) in cancer patients. The research question was formulated according to the PICO framework.
Elaine Cristina Bezerra Bastos, Francisco Samuel Carvalho, Filipe Nobre Chaves, Fábio Wildson Gurgel Costa, Antonio Neudimar Bastos Costa, Camila Melo Mesquita, Maria Raquel Raquel R. Carvalho   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Time spent by infection control professionals undertaking healthcare associated infection surveillance: A multi-centred cross sectional study

, 2016
Background\ud \ud - There is limited contemporary information on how infection control professionals (ICPs) in hospitals utilise their time, with even less providing any specific data on time taken to undertake HAI surveillance.
Mitchell, Brett G., Mitchell, Brett G, Hall, Lisa, MacBeth, Deborough, Halton, Kate, Gardner, Anne   +5 more
core   +1 more source

Distribution and risk factors for Plasmodium and helminth co-infections: a cross-sectional survey among children in Bagamoyo district, coastal region of Tanzania [PDF]

, 2015
Plasmodium and soil transmitted helminth infections (STH) are a major public health problem, particularly among children. There are conflicting findings on potential association between these two parasites.
Abdulla, S, Julian Rothen (716976), Abdulla, Salim, Knopp, S., Mohamed, A., Tanner, M., Daubenberger, C., Mohammed, A.S., Omar Lweno, Stefanie Knopp, Ummi Abdul (716974), Salim, N., Daubenberger, Claudia, Tobias Schindler, Abdulla, S., Abdul, Ummi, Denis Kwaba, Blaise Genton, John Masimba, Nahya Salim (716972), Lweno, Omar, John Masimba (716977), Abdul, U., Kwaba, D., Althaus, F., Rothen, J., Stefanie Knopp (108848), Blaise Genton (67109), Lweno, O., Alisa S Mohammed, Genton, B., Claudia Daubenberger, Kwaba, Denis, Denis Kwaba (716978), Julian Rothen, Mohammed, Alisa S., Salim Abdulla, Mohamed, Ali, Althaus, Fabrice, Schindler, T., Schindler, Tobias, Rothen, Julian, Marcel Tanner (33894), Tobias Schindler (716975), Marcel Tanner, Omar Lweno (716973), Salim Abdulla (76158), Ali Mohamed, Masimba, J., Tanner, Marcel, Genton, Blaise, Masimba, John, Fabrice Althaus (716979), Ali Mohamed (3546578), Alisa S. Mohammed (224862), Nahya Salim, Claudia Daubenberger (212658), Mohammed, S.A., Salim, Nahya, Fabrice Althaus, Knopp, Stefanie, Ummi Abdul   +61 more
core   +1 more source

Incidental Detection of Giardia duodenalis via Cytologic Sampling in Pancreatic Tumor Investigation

Clinical Case Reports
Giardia duodenalis can be incidentally detected during pancreatic tumor evaluation via cytology. Even in asymptomatic patients without risk factors, recognition is essential.
Yoshiro Hadano, Koji Endo
doaj   +1 more source