Results 61 to 70 of about 79,785 (278)

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Recurrence Plot Based Measures of Complexity and its Application to Heart Rate Variability Data

open access: yes, 2002
The knowledge of transitions between regular, laminar or chaotic behavior is essential to understand the underlying mechanisms behind complex systems. While several linear approaches are often insufficient to describe such processes, there are several ...
A. Hempelmann   +34 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Network Analysis of Magnetoencephalogram Signals in Schizophrenia Patients When Viewing Emotional Facial Stimuli

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering, 2023
Schizophrenia is a serious mental disorder. Network analysis of magnetoencephalogram signals may help to identify potential biomarkers of schizophrenia.
Dengxuan Bai   +3 more
doaj   +1 more source

Research into the formation of a soccer curriculum in early childhood education Through the action research with students belonging to IPU’s soccer club and nursery school children [PDF]

open access: yes, 2009
This six-month research examined the influence of playing soccer on the mental and physical development of 5 year old nursery school children under the corporation of students from IPU’s soccer club.
今泉 岳雄   +4 more
core   +1 more source

Inhibition of fatty acid oxidation as a therapy for MYC-overexpressing triple-negative breast cancer. [PDF]

open access: yes, 2016
Expression of the oncogenic transcription factor MYC is disproportionately elevated in triple-negative breast cancer (TNBC), as compared to estrogen receptor-, progesterone receptor- or human epidermal growth factor 2 receptor-positive (RP) breast cancer.
Anderton, Brittany   +11 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Exploration of PET and MRI radiomic features for decoding breast cancer phenotypes and prognosis. [PDF]

open access: yes, 2018
Radiomics is an emerging technology for imaging biomarker discovery and disease-specific personalized treatment management. This paper aims to determine the benefit of using multi-modality radiomics data from PET and MR images in the characterization ...
Arasu, Vignesh A   +13 more
core  

Complex network based techniques to identify extreme events and (sudden) transitions in spatio-temporal systems

open access: yes, 2015
We present here two promising techniques for the application of the complex network approach to continuous spatio-temporal systems that have been developed in the last decade and show large potential for future application and development of complex ...
Kurths, Jürgen, Marwan, Norbert
core   +1 more source

Computational fluid dynamics modeling of symptomatic intracranial atherosclerosis may predict risk of stroke recurrence. [PDF]

open access: yes, 2014
BackgroundPatients with symptomatic intracranial atherosclerosis (ICAS) of ≥ 70% luminal stenosis are at high risk of stroke recurrence. We aimed to evaluate the relationships between hemodynamics of ICAS revealed by computational fluid dynamics (CFD ...
Chen, Xiangyan   +13 more
core   +3 more sources

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