Results 121 to 130 of about 132,516 (260)

First report of Cucumber mosaic virus infecting Ocimum gratissimum (L.) in Calabar, Cross River State, Nigeria. [PDF]

Virusdisease, 2021
Ekpiken EE, Eyong OI, Mofunanya AAJ, Owolabi AT, Arogundade O.   +4 more
europepmc   +1 more source

Extracellular CIRP Dysregulates Microglial Efferocytosis in Acute Ischemic Stroke via the TLR4/miR‐155/MafB Axis

Advanced Science, EarlyView.
eCIRP released in the stroke brain binds to TLR4 expressed on microglia to induce miR‐155, which suppresses MafB, decreases MerTK and downstream signaling to impair efferocytosis of apoptotic neurons, worsening the acute stroke outcomes. Inhibition of eCIRP‐TLR4 interaction with small peptide C23 attenuates eCIRP‐induced microglial efferocytic ...
Dmitriy Lapin, Dilara Aylar, Archna Sharma, Ping Wang   +3 more
wiley   +1 more source

m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress

Advanced Science, EarlyView.
Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang, Ye‐Xin Luo, Cheng‐Fang Sun, Rui Pan, Yu‐Xi Wu, Zhi Yuan, Xin‐Run Wang, Xu‐Dong Zhang, Lan‐Lan Wu, Xiang‐Yu Yao, Zhan‐Dong Song, Wei Chang, Tian Wei, Pan‐Yuan Cai, Tian‐Ci Zhang, Yong‐Wei Xiong, De‐Xiang Xu, Hua Wang, Hua‐Long Zhu   +18 more
wiley   +1 more source

Detecting Schistosoma haematobium infection by microscopy and polymerase chain reaction (PCR) in school children in three senatorial districts of Cross River State, Nigeria. [PDF]

J Parasit Dis, 2022
Esiere RK, Ibeneme EO, Effanga EO, Imalele EE, Esiere MK, Inyang-Etoh PC, Alaribe AAA.   +6 more
europepmc   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

Advanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su, Ye Tian, Fan Zhao, Jing Li, Suryaji Patil, Chunyu Zhu, Yujia Tian, Junrong Wang, Jiating Liu, Aoqi Xiang, Hua Guan, Lusha Zhang, Xiaochang Chen, Airong Qian, Qi Yu   +14 more
wiley   +1 more source

Occupational Exposure and Economic Inequity Along a Game Meat Trade Network in Cross River State, Nigeria. [PDF]

Animals (Basel)
Thompson KET, Herrera CE, Ayambem WA, Alobi AO, Ifebueme NM, Otukpa OM, Aderibigbe TF, Keenan MR, Friant SR.   +8 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Health workers' knowledge, perceptions, and practices relating to antimicrobial use and resistance in cross river state, Nigeria: a cross sectional study. [PDF]

J Health Popul Nutr
Otu AA, Onwusaka OC, Udoh UA, Joel Ugbe UM, Effa EE, Inyang J, Ebenso B, Abdi F, Okwesileze C, Ekeng BE, Ita IO, Walley J.   +11 more
europepmc   +1 more source

Differentiated service delivery models among PLHIV in Akwa Ibom and Cross River States, Nigeria during the COVID-19 pandemic: descriptive analysis of programmatic data. [PDF]

J Int AIDS Soc, 2021
Sanwo O, Persaud NE, Nwaokoro P, Idemudia A, Akpan U, Toyo O, Imohi P, Badru T, Obiora-Okafo C, Uzochukwu CE, Aliu O, Olatunbosun K, Pandey SR, Khamofu H, Chiegil R, James E, Iyortim I, Oqua D, Bateganya M.   +18 more
europepmc   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source