Results 51 to 60 of about 132,516 (260)

Glucosyl Xanthone, d-Idopyranoside, Fatty Acid and Isoprene Derivatives as New Anti-Malarial Compounds Targeting Thymidine Monophosphate Kinase (PfTMPK)

Natural Product Communications
Background Chemotherapy is considered the best approach in the management of malaria pathogenesis symptomized with hyperparasitemia and oxidative stress because of free radicals’ production; however, a crucial step in the production of DNA is the ...
Edet Asanga, Henshaw Okoroiwu, Uwem Edet, Usenobong Ufot, Akaninyene Joseph, Jude Okokon, Promise Nelson, Olorunfemi Eseyin, Ani Nkang, Mfon Akpan, Nikita Umoaffia, Casmir Isienyi, Goodnews Samuel, Samuel Essang, Olamide Kolawole, Tonia Edet, Praise Iwara, Deborah Ani   +17 more
doaj   +1 more source

CT-guided retrieval of a fractured intravenous cannula in a toddler: A case report

African Journal of Emergency Medicine, 2020
Introduction: Fractured cannula is a complication of peripheral intravenous cannula (PIVC) insertion. It is a rare but potentially fatal complication. We present a case of iatrogenic fracture of a PIVC in a toddler.
Peter Olalekan Adeosun, Abdulateef Temitope Abdulazeez, Uchenna Ifeoma Okeke, Olamide Emmanuel Ehinmosan, Eziamaka Gloria Eze   +4 more
doaj   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang, Tianzhen Hua, Meiling Wang, Bingbing Meng, Yue Zhang, Chengxu Jiang, Yunhe Gao, Hongqi Yang, Jian Bo   +8 more
wiley   +1 more source

Effect of Vitamin C on Gasoline Vapor-İnduced Reproductive Toxicity in Female Rats - Original Article

Endocrinology Research and Practice, 2010
Objective: Effect of vitamin C (VC) on gasoline vapor (GV)-induced reproductive toxicity was assessed in female rats using the serum levels of estradiol, progesterone, follicle stimulating hormone (FSH), and luteinizing hormone (LH) as well as the ...
Friday Uboh, Patrick Ebong, Esua Udosen
doaj   +2 more sources

Sonographic evaluation of the impact of umbilical cord insertion site on fetal weight

Ibom Medical Journal
Background: Abnormal insertion of the umbilical cord (UC) into the placenta may initiate fetal growth restriction and potentially complicates labor with intrapartum hemorrhage.
Efanga SA, Akintomide AO, Udofia AT, Obasi UO, Okon OA, Efanga I   +5 more
doaj   +1 more source

Real‐Time and Non‐Invasive Detection of Respiratory Viral Infections Using an Intelligent Odor Monitoring System (IOMS)

Advanced Science, EarlyView.
An intelligent odor monitoring system integrates an IVC animal model, gas sensor array, real‐time resistance readout, and machine‐learning analysis to continuously monitor infection‐associated odor changes. The platform captures longitudinal sensor responses, distinguishes infected from healthy states, and supports early‐stage respiratory viral ...
Yajie Shen, Weifeng Yuan, Long Li, Yucheng Zheng, Kenan Liu, Hegeng Li, Hua‐Yao Li, Yongliang Zhao, Binzhou Ying, Lanpeng Guo, Wenjian Zhang, Shu‐Ming Kuo, Zirui Zhang, Yufan Deng, Bohan Yin, Zhaocheng Luo, Ke Xu, Huan Liu   +17 more
wiley   +1 more source

Public Perception of the Impact of Climate Change on Rainfall Distribution Patterns and Agricultural Production in South-South, Nigeria

Ianna Journal of Interdisciplinary Studies
Background: Climate change is having a profound impact on rainfall patterns, imposing terrifying stresses on agricultural production, particularly in fragile regions like South South Nigeria.
Agnes Offiong, Ndubuisi Bassey Njorkun, Odim Otu Offem, Evelyn Ijeoma Orji , Aganyi Asu Ojong, Anthony Godwin Bullem, Etim Nkanu Efut, Emeka Melvin Amalu, Tpl Simon K. Ajom, Violet Oyo Ekpenyong, Lazarus Bassey Abonor, Doris Elemi Addo, Eno Donatus Uwah, Eyo Orok Edet, Otu Ikoi Ettah, Chinonso Anthony Ofozoba Ofozoba, Dorn Cklaimz Enamhe , Choice Chimaa Okaforcha   +17 more
doaj  

Nano‐Confined Radical Anion as An NIR‐II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination

Advanced Science, EarlyView.
A nano‐confined radical anion acts as a photothermal immunogenic amplifier. Kinetically stabilized nanoparticles couple high near‐infrared‐II (NIR‐II) photothermal efficacy with glutathione (GSH) depletion to boost reactive oxygen species (ROS) and immunogenic cell death (ICD).
Mengxin Mu, Mengyu Guo, Jun Guan, Xiaofeng He, Mingdi Hu, Fene Gao, Klaus Müllen, Chendong Ji, Chunying Chen, Meizhen Yin   +9 more
wiley   +1 more source

Heavy metal profile of water, sediment and freshwater cat fish, Chrysichthys nigrodigitatus (Siluriformes: Bagridae), of Cross River, Nigeria

Revista de Biología Tropical, 2012
Cross River serves as a major source of drinking water, transportation, agricultural activities and fishing in Cross River State, Nigeria. Since there is no formal control of effluents discharged into the river, it is important to monitor the levels of ...
Ezekiel Olatunji Ayotunde, Benedict Obeten Offem, Fidelis Bekeh Ada   +2 more
doaj  

Whole‐Genome Sequencing Pilot of the Central Asian Genomic Diversity Project Reveals Distinct Histories, Adaptation, and Introgression

Advanced Science, EarlyView.
As a pilot phase of the Central Asian Genomic Diversity Project, whole‐genome sequencing of 166 individuals from 20 Central Asian and Afghan Hazara populations reveals fine‐scale substructure shaped by repeated trans‐Eurasian migration and admixture. Integrated analyses uncover post‐admixture adaptation, archaic introgression, and medically relevant ...
Mengge Wang, Shuhan Duan, Qiuxia Sun, Renkuan Tang, Lintao Luo, Jie Zhong, Zhaxylyk Sabitov, CAGDP Consortium†, Lan‐Hai Wei, Chao Liu, Maxat Zhabagin, Guanglin He   +11 more
wiley   +1 more source