Results 101 to 110 of about 124,691 (298)

A Conserved DT2‐bZIP66‐NF‐YC4 Regulatory Module Confers Drought Tolerance in Rice and Arabidopsis

Advanced Science, EarlyView.
This study identifies a conserved tripartiteDT2–bZIP66–NF‐YC4 transcriptional module that enhances rice drought tolerance by activating stress‐responsive genes. This regulatory complex is functionally conserved across cereals and Arabidopsis, providing promising targets for engineering drought‐resilient crops. ABSTRACT Drought stress severely restricts
Jun Shen, Yuchen Li, Liang Zhang, Xiaosong Ma, Chenyin Peng, Chunting Yuan, Yu Wu, Kaiyu Zhao, Sheng Zhao, Jiazhuo Guo, Run Li, Ziqian Yan, Shule Ren, Yige Han, Xin Lin, Xinyue Li, Ming Li, Pingfang Yang, Shiyong Song   +18 more
wiley   +1 more source

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Experimental Validation of the Potential of Cross-Ventilation Strategy as a Natural Cooling Technique Integrated in a Real Historic Building

Applied Sciences
Natural ventilation in hot climates represents a key strategy to reduce the dependence on mechanical cooling systems, especially in historic buildings, where it is essential to balance thermal comfort and heritage conservation.
Teresa Palomo Amores, Francisco Ruda Sarria, Daniel Castro Medina, Teresa Cano Valera, José Sánchez Ramos, Servando Álvarez Domínguez   +5 more
doaj   +1 more source

Cross Ventilation in High-Rise Apartment Building: Effect of Ventilation Shaft Aperture Configuration on Air Velocity and Air Flow Distribution [PDF]

, 2018
Ventilation shaft can be used in apartment units to provide cross ventilation by creating a pressure difference between the room’s windward opening and outlet at the roof. The previous research about ventilation shaft has shown its potential in providing
Fahmi, M. Rizal; Department of Architecture, Faculty of Architecture, Design, and Planning, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia, Antaryama, I. Gusti Ngurah; Department of Architecture, Faculty of Architecture, Design, and Planning, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia, Defiana, Ima; Department of Architecture, Faculty of Architecture, Design, and Planning, Institut Teknologi Sepuluh Nopember (ITS), Kampus ITS Sukolilo, Surabaya 60111, Indonesia   +2 more
core   +2 more sources

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Evaluation of Airborne Infection Risk in a School Using Multizone Simulation: Pathogen Transmission Between Students in Different Classrooms Through Corridors

Aerosol and Air Quality Research
Background Airborne infections in school environments are influenced not only by conditions within individual classrooms but also by pathogen transmission through shared spaces such as corridors. Effective ventilation strategies are essential to mitigate
Sungjae Park, Jungwoo Park, Jungho Hwang
doaj   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

Advanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun, Bo Jia, Jiahui Shi, Shuang Li, Guo Bao, Dong Bian, Kai Chen, Junlong Tan, Xuenan Gu, Yan Guan, Yu Qin, Xinhua Qu, Xiaogang Wang, Yufeng Zheng, Hongtao Yang   +14 more
wiley   +1 more source

A Multi-Scale BIM-Driven Framework for Predictive Ventilation Opportunity Mapping and Performance Optimization in Low-Rise Sustainable Buildings

Buildings
Natural ventilation remains a key strategy for improving indoor environmental quality (IEQ), lowering energy demand, and increasing resilience in low-rise residential buildings, especially in warm climates where mechanical ventilation is costly or ...
Oriah Mudondo, Chunyan Yuan, Chengyu Zhang, Xueyuan Sun, Yan Wang   +4 more
doaj   +1 more source

CFD simulation of cross-ventilation in buildings using rooftop wind-catchers: Impact of outlet openings [PDF]

, 2018
Cross-ventilation using rooftop wind-catchers is very complex as it is influenced by a wide range of interrelated factors including aerodynamic characteristics of the wind catcher, approach-flow conditions and building geometry.
Montazeri, H.; id_orcid, F. Montazeri, Montazeri, F., H. Montazeri, Montazeri, H., Montazeri, H Hamid, Montazeri, Fatemeh, Montazeri, Hamid   +7 more
core   +1 more source