Results 31 to 40 of about 2,071 (101)

CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions

Glia, Volume 74, Issue 10, October 2026.
CX3CR1 deficiency promotes microglial migration toward CNS injury. Proteomic profiling reveals altered RHO‐mediated cytoskeletal signaling, while in vivo two‐photon imaging demonstrates increased process extension, velocity, and accumulation of Cx3cr1‐deficient microglia at lesion sites. ABSTRACT Microglia are innate immune cells of the central nervous
Jens Wagner, Henrike Antony, Cornelia Hoyer, Kristiina Lundgrén, Rabah Soliymani, Sophie Crux, Lena Justus, Kevin Keppler, Julia Steffen, Christian Kurts, Daniel R. Engel, Jochen Herms, Maciej Łałowski, Martin Fuhrmann   +13 more
wiley   +1 more source

Conserved and Tissue‐Specific RNA and Protein Cargos of Small Extracellular Vesicles From 120 Tissue Sites Across 34 Organs in a Single Pig

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
A whole‐body map of sEVs from a single pig, including 133 samples spanning 10 systems, revealed striking tissue‐specific heterogeneity in yield. Importantly, a conserved core cargo set comprising candidate sEV markers (ACTG1, CFL1, and ANXA2), RNA‐binding proteins, the let‐7 miRNA family, and ferritin genes was defined from 105,409 (88.6% full‐length ...
Naixiang Yu, Jinxiu Liu, Chenliang Lai, Siyi Liu, Jiacheng Wei, Jiahong Zhong, Sanya Xiong, Qingjie Zeng, Junwu Ma, Zhou Zhang, Zhiyan Zhang   +10 more
wiley   +1 more source

Extracellular Vesicle‐Encapsulated Small RNAs From Clostridium Butyricum Modulate Host Intestinal Lipid Metabolism

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
Extracellular vesicles (EVs) derived from C. butyricum can enter intestinal epithelial cells and mediate the anti‐lipid absorption effects by delivering miRNA‐like RNAs (milRNAs), particularly milRNA‐3020179, which primarily targeted host genes majorly including PPARα. Deletion of milRNA‐3020179 in C. butyricum abolished its effects on lipid deposition
Hong Hu, Yiwen He, Jing Liang, Qi Han, Xuqing Liang, Guangtian Cao, Yulong Tang, Liuqin He, Yulong Yin, Xihong Zhou   +9 more
wiley   +1 more source

Livestock Multi‐Omics Integration: A Systematic Framework From Statistical Association to Causal Interpretation

Advanced Science, Volume 13, Issue 50, 7 September 2026.
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen, Zhongyu Wang, Jieping Huang, Fen Li, Ningbo Chen, Yun Ma   +5 more
wiley   +1 more source

Successful Identification of Duck Genome Region Determining Desirable Uniformity of Meat Performance Traits

Brazilian Journal of Poultry Science
The objective of this study was to identify genome regions determining duck meat performance traits with possible small variation. In total, 368 crossbred ducks of F2 generation obtained from two parental lines: Pekin-type ducks of Polish origin (A55 ...
A Dobek, E Gornowicz, K Moliński, B Grajewski, M Lisowski, T Szwaczkowski   +5 more
doaj   +1 more source

Mining rare haplotypes to accelerate precision breeding in rice

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Rice (Oryza sativa L.) genomics has made significant progress, with over 13000 genome sequences available and more than 4500 genes functionally characterized. However, limited haplotype‐level information has constrained the effective deployment of these genes in breeding programs.
Swati Tyagi, Anoop Kishor Singh Gurjar, Sonali Vijay Habde, Krishna Tesman Sundaram, Namrata Devidas Patil, Diksha Rai, Ajay Bogati, Pronob J. Paul, Ankur Kumar Singh, Ajay Tripathi, Sanjay Kalia, Ajay Kohli, Arvind Kumar, Pallavi Sinha, Uma Maheshwar Singh, Vikas Kumar Singh   +15 more
wiley   +1 more source

Characterizing the Milk Microbiome in Subclinical Mastitis: A Pilot 16S rRNA‐Based Study in Cattle and Water Buffalo

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Milk samples collected from cattle and buffalo were pooled and screened for mastitis prior to DNA extraction. Sequencing of the V1–V7 region of 16S rRNA was performed using the MinION platform, and the resulting data were analysed to determine taxonomic classification and assess microbial diversity. ABSTRACT Background In the dairy sector of Bangladesh,
Md. Habib Ullah Masum, Maksudur Rahman Nayem, Ahmad Abdullah Mahdeen, Sumaia Sultana, Abanti Barua   +4 more
wiley   +1 more source

Taxonomic inflation in fish systematics: A critical review with illustrative evidence assessment and integrative case study of the Salmo trutta Complex

Journal of Fish Biology, Volume 109, Issue 3, Page 1360-1378, September 2026.
Abstract Fish species are being described at an accelerating rate, but a substantial fraction of recent descriptions rests on evidentiary standards too weak to distinguish genuine species‐level discontinuities from intraspecific variation, local adaptation and the artefacts of single‐marker analyses, a pattern of taxonomic inflation with documented ...
Ilhan Altinok
wiley   +1 more source

Genetic analysis of efficiency-related traits in Boer x Central Highland goats.

PLoS ONE
This study aimed to identify important non-genetic factors and estimate genetic parameters for efficiency-related traits in Boer x Central Highland goats.
Zeleke Tesema, Kefyalew Alemayehu, Tesfaye Getachew, Damitie Kebede, Mekonnen Tilahun, Belay Deribe, Mesfin Lakew, Getachew Worku Alebachew, Mengistie Taye, Solomon Gizaw   +9 more
doaj   +1 more source

Activity-based first estrus detection in grazing heifers and first-lactation dairy cows for use as novel fertility phenotypes at scale

Frontiers in Animal Science
Timing of first detected estrus of peripubertal heifers and postpartum dairy cows is an informative predictor of reproductive performance with potential to support genetic gain in fertility.
Simon J. R. Woodward, Daniel P. Garrick, Nicole M. Steele, Nicole M. Steele, Melissa A. Stephen, Melissa A. Stephen, Claire V. C. Phyn, Susanne Meier, Chris R. Burke   +8 more
doaj   +1 more source